Please wait a minute...

Frontiers of Optoelectronics

Front Optoelec Chin    2009, Vol. 2 Issue (3) : 248-252     DOI: 10.1007/s12200-009-0050-8
Portable muscle oxygenation monitor based on near infrared spectroscopy
Zhongxing ZHANG, Bangde WANG, Qing NIE, Qingming LUO, Hui GONG()
Britton Chance Center for Biomedical Photonics, Wuhan National Laboratory for Optoelectronics, Huazhong University of Science and Technology, Wuhan 430074, China
Download: PDF(143 KB)   HTML
Export: BibTeX | EndNote | Reference Manager | ProCite | RefWorks

In order to measure the relative change of muscle oxygenation non-invasively, dynamically and directly, a portable monitor based on near infrared spectroscopy (NIRS) was developed. The monitor consists of several function modules, including 735 nm, 805 nm and 850 nm integrated three-wavelength light emitting diode (LED) light source, LED driver, integrated detector, amplifier and filter, A/D sampling circuit, single chip microcomputer and laptop. The distance between light source and detector is 3 cm and the photon migration depth in tissue is approximately 1.5 cm. The monitor is portable with low dark noise and good long-term stability. The relative change of muscle oxygenation measured by the monitor was in accordance with the real physiology status in the cuff ischemia experiment, verifying the performance of the monitor for living muscle. Two inflexions referring to an accelerated fall and a leveling-off phase in the muscle oxygenation index, respectively, were observed in in vivo incremental intensity exercises. Significant correlation was found between the first inflexion and the ventilatory threshold which was identified by the gas exchange measurement. These results demonstrated that the monitor can be used to detect the local lactate threshold of the measured muscle and reflect the changes of oxygen index in local muscle for in vivo exercises. The monitor may provide a meaningful approach to evaluate the subject’s oxidative capacity effectively.

Keywords near infrared spectroscopy (NIRS)      muscle oxygenation      lactate threshold (LAT)      exercise     
Corresponding Authors: GONG Hui,   
Issue Date: 05 September 2009
 Cite this article:   
Zhongxing ZHANG,Bangde WANG,Qing NIE, et al. Portable muscle oxygenation monitor based on near infrared spectroscopy[J]. Front Optoelec Chin, 2009, 2(3): 248-252.
E-mail this article
E-mail Alert
Articles by authors
Zhongxing ZHANG
Bangde WANG
Qing NIE
Qingming LUO
Fig.1  Photograph of NIRS muscle oxygenation monitor
Fig.2  Block diagram of NIRS muscle oxygenation monitor
Fig.3  Blood volume and oxygenation change in cuff ischemia
Fig.4  Typical results of incremental intensity exercise. (a) Changes of muscle oxygenation in right vastus lateralis muscle; (b) changes of respiratory parameters
1 Wasserman K, Whipp B J, Koyl S N, Beaver W L. Anaerobic threshold and respiratory gas exchange during exercise. Journal of Applied Physiology , 1973, 35(2): 236–243
2 McArdle W D, Katch F I, Katch V L. Exercise Physiology: Energy, Nutrition, and Human Performance. Baltimore: Lippincott Williams & Wilkins, 1996, 469–508
3 Pei J, Yang J C. On the progress of the measuring method of anaerobic threshold. Journal of Capital Institute of Physical Education , 2006, 18(6): 68–70 (in Chinese)
4 Yang X R. Practical Exercise Physiology. Beijing: Beijing Institute of Physical Education Press, 1998, 138–148 (in Chinese)
5 Yeh M P, Gardner R M, Adams T D, Yanowitz F G, Crapo R O. “Anaerobic threshold”: problems of determination and validation. Journal of Applied Physiology , 1983, 55(4):1178–1186
6 Chance B, Luo Q, Nioka S, Alsop D C, Detre J A. Optical investigations of physiology: a study of intrinsic and extrinsic biomedical contrast. Philosophical Transactions of the Royal Society of London , 1997, 352(1354): 707–716
doi: 10.1098/rstb.1997.0053
7 Chance B, Dait M T, Zhang C, Hamaoka T, Hagerman F. Recovery from exercise-induced desaturation in the quadriceps muscles of elite competitive rowers. American Journal of Physiology , 1992, 262(3): C766–C775
8 Ferrari M, Mottola L, Quaresima V. Principles, techniques, and limitations of near infrared spectroscopy. Canadian Journal of Applied Physiology , 2004, 29(4): 463–487
9 Xu G D, Luo Q M. A study on the relationship between blood acid lactate in motion and hemoglobin saturation density. Journal of Wuhan Institute of Physical Education , 2001, 35(3): 40–42 (in Chinese)
10 Bhambhani Y N. Muscle oxygenation trends during dynamic exercise measured by near infrared spectroscopy. Canadian Journal of Applied Physiology , 2004, 29(4): 504–523
11 Hamaoka T, McCully K K, Quaresima V, Yamamoto K, Chance B. Near-infrared spectroscopy/imaging for monitoring muscle oxygenation and oxidative metabolism in healthy and diseased humans. Journal of Biomedical Optics , 2007, 12(6): 062105
doi: 10.1117/1.2805437
12 Lin Y Q, Lech G, Nioka S, Intes X, Chance B. Noninvasive, low-noise, fast imaging of blood volume and deoxygenation changes in muscles using light-emitting diode continuous-wave imager. Review of Scientific Instruments , 2002, 73(8): 3065–3074
doi: 10.1063/1.1485779
13 Beaver W L, Wasserman K, Whipp B J. A new method for detecting anaerobic threshold by gas exchange. Journal of Applied Physiology , 1986, 60(6): 2020–2027
14 Legrand R, Marles A, Prieur F, Lazzari S, Blondel N, Mucci P. Related trends in locomotor and respiratory muscle oxygenation during exercise. Medicine and Science in Sports and Exercise , 2007, 39(1): 91–100
doi: 10.1249/01.mss.0000241638.90348.67
Related articles from Frontiers Journals
[1] Yuxiang WU,Tao SONG,Guodong XU. Changes of muscle oxygenation and blood lactate concentration of swimming athletes during graded incremental exercise[J]. Front. Optoelectron., 2015, 8(4): 451-455.
Full text