A single session of strength training changed plasma levels of resistin, but not leptin in overweight and obese men

Abstract

Obesity has a complex multifactorial etiology and is characterized by excessive accumulation of adipose tissue. Visceral adipose tissue has deleterious effects on health because it secretes large amounts of inflammatory cytokines. Nutritional calorie restriction associated with strength training may be useful in managing chronic systemic inflammation. This study aimed to evaluate the acute effect of a single strength-training session on plasma adipokine levels in sedentary, overweight, and obese young men. This study included twelve men (Age: [34.95 ​± ​9.77] years; Height: [174.16 ​± ​3.66] centimeter [cm]; Weight: [97.83 ​± ​12.87] kilogram (kg); body mass index [BMI]: [32.30 ​± ​4.51] kg/m²), who performed a single strength training session. The strength training protocol consisted of 4 sets of 12 repetitions in the following six exercises, 45° leg press, bench press, leg extension, machine row, leg curl, and shoulder press. Blood samples were collected before, immediately after, and 1-h subsequent after strength training. The plasma levels of resistin and leptin were measured. A significant decrease in resistin levels were found 1 ​h after the strength training session if compared to levels before the training session (pre-[before] [2 390 ​± ​1 199] picograms per milliliter [pg/mL] vs post-1 h [1-h subsequent] [1 523 ​± ​798],6 ​pg/mL, p ​= ​0.002 8). The plasma leptin levels did not differ at any time point. In conclusion, a very well controlled single session of strength training significantly decreased the plasma levels of resistin without altering the concentration of leptin in overweight and obese individuals. This effect, at least in part, supports the benefits of exercise by reducing the low grade inflammation and insulin resistance in obesity.

Keywords

Strength training / Adipose tissue / Obesity / Chronic inflammation / Resistin / Leptin

Ethics approval statement

The study was approved by the Ethics Committee of Ouro Preto Federal University (CAAE no. 42886621.4.0000.5150 and approval no. 4.693.684) according to the criteria of the Brazilian legislation for studies on human beings and the resolution of the National Health Council 466/12. The informed consent was obtained from each participant, and the study was reviewed by the author's institution and received approval to implement the study. The informed consent was collected from each participant in this study.

Authors’ contribution

Yago Martins Fortes: Conceptualization, Data curation. Antonio Felipe Souza-Gomes: Writing - original draft, Writing - review & editing. Alessandro Roberto Silveira Moreira: Data curation, Investigation. Leo Nogueira Campos: Formal analysis, Investigation. Samara Silva de Moura: Formal analysis. Lucélia Scarabeli Silva Barroso: Formal analysis. Marcelo Henrique Salviano de Faria: Writing - original draft. Heliana de Barros Fernandes: Formal analysis. Aline Silva de Miranda: Formal analysis, Funding acquisition, Writing - original draft. Hugo César Martins-Costa: Writing - original draft. Ana Cristina Simões e Silva: Conceptualization, Data curation, Formal analysis, Methodology, Writing - original draft, Writing - review & editing. Janaina Matos Moreira: Conceptualization, Data curation, Funding acquisition, Supervision, Writing - original draft, Writing - review & editing. Albená Nunes-Silva: Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Writing - original draft, Writing - review & editing.

Conflict of interest

Authors declare on conflict of interest.

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