Chronic hemodynamic adaptations induced by resistance training with and without blood flow restriction in adults: A systematic review and meta-analysis

Allison Russo, Giorjines Boppre, Cristine Schmidt, Lucimere Bohn

Sports Medicine and Health Science ›› 2023, Vol. 5 ›› Issue (4) : 259-268. DOI: 10.1016/j.smhs.2023.09.006
Review

Chronic hemodynamic adaptations induced by resistance training with and without blood flow restriction in adults: A systematic review and meta-analysis

Author information +
History +

Abstract

The purposes of this systematic review and meta-analysis of peer-reviewed literature were to examine the chronic effects of resistance training with blood flow restriction (RT-BFR) on hemodynamics, and to compare these adaptations to those induced by traditional resistance training (TRT) programs in adults (PROSPERO: Registry: CRD42022339510). A literature search was conducted across PubMed, Sports Discus, Scielo, and Web of Science databases. Two independent reviewers extracted study characteristics and blood pressure measures. Risk of bias (The Cochrane risk of bias tool for randomized controlled trials [RoB-2]), and the certainty of the evidence (Grading of Recommendations, Assessment, Development, and Evaluation [GRADE]) were used. A total of eight studies met the inclusion criteria for systolic (SBP), diastolic (DBP), and mean arterial pressure (MAP). Regarding the comparison of RT-BFR vs. non-exercise, no significant differences favoring the exercise group were observed (p ​> ​0.05). However, when compared to TRT, RT-BFR elicited additional improvements on DBP (−3.35; 95%CI -6.00 to −0.71; I2 ​= ​14%; z ​= ​−2.48, p ​= ​0.01), and on MAP (−3.96; 95%CI -7.94 to 0.02; I2 ​= ​43%; z ​= ​−1.95, p ​= ​0.05). Results indicate that RT-BFR may elicit a decrease in DBP in comparison with TRT, but the lack of data addressing this topic makes any conclusion speculative. Future research on this topic is warranted.

Keywords

Strength training / Blood flow restriction / Blood pressure / Chronic effect

Cite this article

Download citation ▾
Allison Russo, Giorjines Boppre, Cristine Schmidt, Lucimere Bohn. Chronic hemodynamic adaptations induced by resistance training with and without blood flow restriction in adults: A systematic review and meta-analysis. Sports Medicine and Health Science, 2023, 5(4): 259‒268 https://doi.org/10.1016/j.smhs.2023.09.006

References

[[1]]
B.R. Scott, J.P. Loenneke, K.M. Slattery, B.J. Dascombe. Exercise with blood flow restriction: an updated evidence-based approach for enhanced muscular development. Sports Med, 45 (3) ( 2015), pp. 313-325, DOI: 10.1007/s40279-014-0288-1
[[2]]
Z.K. Pope, J.M. Willardson, B.J. Schoenfeld. Exercise and blood flow restriction. J Strength Cond Res, 27 (10) ( 2013), pp. 2914-2926, DOI: 10.1519/JSC.0b013e3182874721
[[3]]
S.D. Patterson, L. Hughes, S. Warmington, et al.. Blood flow restriction exercise: considerations of methodology, application, and safety. Front Physiol, 10 ( 2019), p. 533, DOI: 10.3389/fphys.2019.00533
[[4]]
M.E. Lixandrão, C. Ugrinowitsch, G. Laurentino, et al.. Effects of exercise intensity and occlusion pressure after 12 weeks of resistance training with blood-flow restriction. Eur J Appl Physiol, 115 (12) ( 2015), pp. 2471-2480, DOI: 10.1007/s00421-015-3253-2
[[5]]
B.C. Miller, A.W. Tirko, J.M. Shipe, O.R. Sumeriski, K. Moran. The systemic effects of blood flow restriction training: a systematic review. Int J Sports Phys Ther, 16 (4) ( 2021), pp. 978-990, DOI: 10.26603/001c.25791
[[6]]
J. Slysz, J. Stultz, J.F. Burr. The efficacy of blood flow restricted exercise: a systematic review & meta-analysis. J Sci Med Sport, 19 (8) ( 2016), pp. 669-675, DOI: 10.1016/j.jsams.2015.09.005
[[7]]
W.R. Vanwye, A.M. Weatherholt, A.E. Mikesky. Blood flow restriction training: implementation into clinical practice. Int Exerc Sci, 10 (5) ( 2017), pp. 649-654, DOI: 10.1007/s40279-014-0288-1
[[8]]
C. Centner, P. Wiegel, A. Gollhofer, D. König. Effects of blood flow restriction training on muscular strength and hypertrophy in older individuals: a systematic review and meta-analysis. Sports Med, 49 (1) ( 2019), pp. 95-108, DOI: 10.1007/s40279-018-0994-1
[[9]]
T.C. Alves, A.P. Santos, P.P. Abdalla, et al.. Resistance training with blood flow restriction: impact on the muscle strength and body composition in people living with HIV/AIDS. Eur J Sport Sci, 21 (3) ( 2021), pp. 450-459, DOI: 10.1080/17461391.2020.1757765
[[10]]
B.R. Scott, J.J. Peiffer, H.J. Thomas, K.J. Marston, K.D. Hill.Hemodynamic responses to low-load blood flow restriction and unrestricted high-load resistance exercise in older women. Front Physiol, 9 ( 2018), p. 1324, DOI: 10.3389/fphys.2018.01324
[[11]]
E. Domingos, M.D. Polito. Blood pressure response between resistance exercise with and without blood flow restriction: a systematic review and meta-analysis. Life Sci, 209 ( 2018), pp. 122-131, DOI: 10.1016/j.lfs.2018.08.006
[[12]]
M.J. Page, J.E. McKenzie, P.M. Bossuyt, et al.. The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. BMJ, 372 ( 2021), p. n71, DOI: 10.1136/bmj.n71
[[13]]
J.P.T. Higgins, J. Thomas, J. Chandler, et al.. Cochrane Handbook for Systematic Reviews of Interventions. Wiley ( 2019)
[[14]]
J.A.C. Sterne, J. Savović, M.J. Page, et al.. RoB 2: a revised tool for assessing risk of bias in randomised trials. BMJ, 366 ( 2019), p. l4898, DOI: 10.1136/bmj.l4898
[[15]]
H. Schünemann, J. Brożek, G. Guyatt, A. Oxman. Handbook for Grading the Quality of Evidence and the Strength of Recommendations Using the GRADE Approach. ( 2013)
[[16]]
J.A. Sterne, A.J. Sutton, J.P. Ioannidis, et al.. Recommendations for examining and interpreting funnel plot asymmetry in meta-analyses of randomised controlled trials. BMJ, 343 ( 2011), p. d4002, DOI: 10.1136/bmj.d4002
[[17]]
G. Schwarzer, J.R. Carpenter,G. Rücker. Meta-analysis with R. Springer ( 2015)
[[18]]
M.A. Cezar, C.A. De , VdS. Corralo, S.L. Copatti,GAGd Santos, MEdS. Grigoletto. Effects of exercise training with blood flow restriction on blood pressure in medicated hypertensive patients. Motriz: Rev Educ Fis., 22 ( 2016), pp. 9-17, DOI: 10.1590/S1980-6574201600020002
[[19]]
H.G. Silva, M.S. Cirilo-Sousa, G.R. Neto, L.F. Vieira, M.M. Brasiliano, R.C. Araújo. Efeito agudo e crônico do treinamento de força com restrição de fluxo sanguíneo contínua ou intermitente sobre as medidas hemodinâmicas e percepção subjetiva de esforço em homens saudáveis. Motricidade, 14 (1S) ( 2018), pp. 71-82, DOI: 10.6063/motricidade.14610
[[20]]
Y. Zhao, A. Lin, L. Jiao. Eight weeks of resistance training with blood flow restriction improve cardiac function and vascular endothelial function in healthy young Asian males. Int Health, 13 (5) ( 2021), pp. 471-479, DOI: 10.1093/inthealth/ihaa089
[[21]]
H. Ozaki, T. Yasuda, R. Ogasawara, M. Sakamaki-Sunaga, H. Naito, T. Abe. Effects of high-intensity and blood flow-restricted low-intensity resistance training on carotid arterial compliance: role of blood pressure during training sessions. Eur J Appl Physiol, 113 (1) ( 2013), pp. 167-174, DOI: 10.1007/s00421-012-2422-9
[[22]]
T. Yasuda, K. Fukumura, T. Fukuda, et al.. Muscle size and arterial stiffness after blood flow-restricted low-intensity resistance training in older adults. Scand J Med Sci Sports, 24 (5) ( 2014), pp. 799-806, DOI: 10.1111/sms.12087
[[23]]
T. Yasuda, K. Fukumura, Y. Uchida, et al.. Effects of low-load, elastic band resistance training combined with blood flow restriction on muscle size and arterial stiffness in older adults. J Gerontol A Biol Sci Med Sci, 70 (8) ( 2015), pp. 950-958, DOI: 10.1093/gerona/glu084
[[24]]
K.S. Early, M. Rockhill, A. Bryan, B. Tyo, D. Buuck, J. McGinty. Effect of blood flow restriction training on muscular performance, pain and vascular function. Int J Sports Phys Ther, 15 (6) ( 2020), pp. 892-900, DOI: 10.26603/ijspt20200892
[[25]]
C.A. Fahs, L.M. Rossow, J.P. Loenneke, et al.. Effect of different types of lower body resistance training on arterial compliance and calf blood flow. Clin Physiol Funct Imaging, 32 (1) ( 2012), pp. 45-51, DOI: 10.1111/j.1475-097X.2011.01053.x
[[26]]
V.A. Cornelissen, N.A. Smart. Exercise training for blood pressure: a systematic review and meta-analysis. J Am Heart Assoc, 2 (1) ( 2013), Article e004473, DOI: 10.1161/jaha.112.004473
[[27]]
T.C. Alves, P. Pugliesi Abdalla, L. Bohn, et al.. Acute and chronic cardiometabolic responses induced by resistance training with blood flow restriction in HIV patients. Sci Rep, 12 (1) ( 2022), Article 16989, DOI: 10.1038/s41598-022-19857-3
[[28]]
M. Horiuchi, K. Okita. Blood flow restricted exercise and vascular function. Int J Vasc Med, 2012 ( 2012), Article 543218, DOI: 10.1155/2012/543218
[[29]]
M.S. Cerqueira, E.C. Costa, R. Santos Oliveira, R. Pereira, W.H. Brito Vieira. Blood flow restriction training: to adjust or not adjust the cuff pressure over an intervention period?. Front Physiol, 12 ( 2021), Article 678407, DOI: 10.3389/fphys.2021.678407
[[30]]
H.V. MacDonald, B.T. Johnson, T.B. Huedo-Medina, et al.. Dynamic resistance training as stand-alone antihypertensive lifestyle therapy: a meta-Analysis. J Am Heart Assoc, 5 (10) ( 2016), Article e003231, DOI: 10.1161/jaha.116.003231

Accesses

Citations

Detail

Sections
Recommended

/