Neither autophagy nor exercise training mode affect exercise-induced beneficial adaptations in high fat-fed mice

Megan E. Rosa-Caldwell, Lisa T. Jansen, Seongkyun Lim, Kirsten R. Dunlap, Wesley S. Haynie, Tyrone A. Washington, Nicholas P. Greene

Sports Medicine and Health Science ›› 2020, Vol. 2 ›› Issue (1) : 44-53.

Sports Medicine and Health Science ›› 2020, Vol. 2 ›› Issue (1) : 44-53. DOI: 10.1016/j.smhs.2020.03.003
Original article

Neither autophagy nor exercise training mode affect exercise-induced beneficial adaptations in high fat-fed mice

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Abstract

Exercise mitigates obesity-associated pathologies; however, there is controversy regarding optimal exercise interventions. Autophagy, is known to decrease during obesity and is an important moderator for exercise adaptations.

Conclusions

Keywords

Insulin resistance / Exercise capacity / Glucose tolerance / Obesity

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Megan E. Rosa-Caldwell, Lisa T. Jansen, Seongkyun Lim, Kirsten R. Dunlap, Wesley S. Haynie, Tyrone A. Washington, Nicholas P. Greene. Neither autophagy nor exercise training mode affect exercise-induced beneficial adaptations in high fat-fed mice. Sports Medicine and Health Science, 2020, 2(1): 44‒53 https://doi.org/10.1016/j.smhs.2020.03.003

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This study was funded by the Central States Chapter of the American College of Sports Medicine and The University of Arkansas Human Health, Performance and Recreation Departmental Graduate Student Grant. The authors would like to thank the hard working students, faculty and staff at the Exercise Science Research Center for their continual support of our research.

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