Conventional surgical techniques and emerging transplantation in complex penile reconstruction

Nima Khavanin , Richard J. Redett

Plastic and Aesthetic Research ›› 2020, Vol. 7 ›› Issue (1) : 47

PDF
Plastic and Aesthetic Research ›› 2020, Vol. 7 ›› Issue (1) :47 DOI: 10.20517/2347-9264.2020.63
Review
Review
Conventional surgical techniques and emerging transplantation in complex penile reconstruction
Author information +
History +
PDF

Abstract

Complex penile reconstruction continues to pose a significant challenge to surgeons and patients alike. The ideal phalloplasty is one that can be reproducibly performed in a single stage, creates a neourethra that allows for voiding while standing, produces a phallus with tactile and erogenous sensation, allows for penetrative sexual intercourse, and offers satisfactory aesthetic results. With recent advances in microsurgery and perforator flap dissection, several techniques and modifications thereof have been described that aim to achieve these reconstructive goals. All of these now conventional techniques, however, fall short in one way or another - often with regards to urinary transport, the ability to achieve an erection, and the need for multiple surgical stages and revision operations. These limitations of conventional reconstruction have led some surgeons to explore new avenues for complex penis reconstruction, giving birth to the novel field of penile transplantation. In this article, we discuss the complexities of male genitourinary reconstruction in the context of conventional methods for reconstruction as well as the burgeoning field of penile transplantation.

Keywords

Phalloplasty / total penile reconstruction / free flap / vascularized composite allotransplantation / penis transplantation / reconstructive surgery / urologic reconstruction

Cite this article

Download citation ▾
Nima Khavanin, Richard J. Redett. Conventional surgical techniques and emerging transplantation in complex penile reconstruction. Plastic and Aesthetic Research, 2020, 7(1): 47 DOI:10.20517/2347-9264.2020.63

登录浏览全文

4963

注册一个新账户 忘记密码

References

[1]

Bogoraz N.On complete plastic reconstruction of a penis sufficient for coitus..Sov Surg1936;8:303-9

[2]

Gillies SH.Congenital absence of the penis..Br J Plast Surg1948;1:8-28

[3]

Yao A,Lopez CD,Burish NM.Total penile reconstruction: a systematic review..J Plast Reconstr Aesthet Surg2018;71:788-806

[4]

Kropp B,Wang W,Ducic Y.Free tissue transfer penile reconstruction..Semin Plast Surg2019;33:24-9 PMCID:PMC6408249

[5]

Salmerón-González E,García-Vilariño E,Pérez-García A.Technical detail on nerve coaptation in phalloplasty: use of fibrin glue instead of sutures..Sex Med Rev2019;7:376

[6]

Massanyi EZ,Goel S,Burnett AL.Radial forearm free flap phalloplasty for penile inadequacy in patients with exstrophy..J Urol2013;190:1577-82

[7]

Redett RJ3rd,Brandacher G,Tuffaha SH.Total penis, scrotum, and lower abdominal wall transplantation..N Engl J Med2019;381:1876-8

[8]

Cetrulo CL Jr,Salinas HM,Schol I.Penis transplantation: first US experience..Ann Surg2018;267:983-8

[9]

Bateman C.World’s first successful penis transplant at Tygerberg Hospital..S Afr Med J2015;105:251-2

[10]

Hu W,Zhang L,Nie H.A preliminary report of penile transplantation: part 2..Eur Urol2006;50:1115-6discussion 1116

[11]

Hu W,Zhang L,Nie H.A preliminary report of penile transplantation..Eur Urol2006;50:851-3

[12]

Siegel RL,Jemal A.Cancer statistics, 2018..CA Cancer J Clin2018;68:7-30

[13]

Ornellas AA.Management of penile cancer..J Surg Oncol2008;97:199-200

[14]

Pow-Sang MR,Pow-Sang JM,Destefano V.Epidemiology and natural history of penile cancer..Urology2010;76:S2-6

[15]

Hudak SJ,Rozanski TA.Battlefield urogenital injuries: changing patterns during the past century..Urology2005;65:1041-6

[16]

Tuffaha SH,Sopko NA,Lough DM.Penile transplantation: an emerging option for genitourinary reconstruction..Transpl Int2017;30:441-50

[17]

Janak JC,Soderdahl DW.Epidemiology of genitourinary injuries among male U.S. service members deployed to iraq and afghanistan: early findings from the trauma outcomes and urogenital health (TOUGH) project..J Urol2017;197:414-9

[18]

The Williams Institute. How many adults identify as transgender in the United States? Available from: https://williamsinstitute.law.ucla.edu/wp-content/uploads/How-Many-Adults-Identify-as-Transgender-in-the-United-States. [Last accessed on 5 Aug 2020]

[19]

Bluebond-Langner R.Phalloplasty in complete aphallia and ambiguous genitalia..Semin Plast Surg2011;25:196-205 PMCID:PMC3312182

[20]

Gearhart JP.Wein AJ,Novick AC,Peters CA.Exstrophy-epispadias complex..Campbell-Walsh Urology.2007;9th edPhiladelphiaSaunders3497-555

[21]

Tuffaha SH,Shores JT,Lee WP.Using the dorsal, cavernosal, and external pudendal arteries for penile transplantation: technical considerations and perfusion territories..Plast Reconstr Surg2014;134:111e-9

[22]

Gilbert DA.Penis construction..Semin Urol1987;5:262-9

[23]

Monstrey S,Selvaggi G,Van Landuyt K.Penile reconstruction: is the radial forearm flap really the standard technique?.Plast Reconstr Surg2009;124:510-8

[24]

Satteson ES,Waltonen JD,Wiesler ER.Donor-site outcomes for the osteocutaneous radial forearm free flap..J Reconstr Microsurg2017;33:544-8

[25]

Biemer E.Penile construction by the radial arm flap..Clin Plast Surg1988;15:425-30

[26]

Garaffa G,Christopher NA.Total phallic reconstruction after penile amputation for carcinoma..BJU Int2009;104:852-6

[27]

Ma S,Liu Y.Sensibility following innervated free radial forearm flap for penile reconstruction..Plast Reconstr Surg2011;127:235-41

[28]

Rubino C,Dessy LA,Mazzocchi M.Innervated island pedicled anterolateral thigh flap for neo-phallic reconstruction in female-to-male transsexuals..J Plast Reconstr Aesthet Surg2009;62:e45-9

[29]

Mutaf M.A new surgical procedure for phallic reconstruction: istanbul flap..Plast Reconstr Surg2000;105:1361-70

[30]

Mutaf M,Bulut O.A true one-stage nonmicrosurgical technique for total phallic reconstruction..Ann Plast Surg2006;57:100-6

[31]

Morrison SD,Vyas KS,Crane CN.Phalloplasty: a review of techniques and outcomes..Plast Reconstr Surg2016;138:594-615

[32]

Dabernig J,Schaff J.Phalloplasty with free (septocutaneous) fibular flap sine fibula..J Urol2006;176:2085-8

[33]

Hage JJ,Van Lieshout J.Fibula free flap phalloplasty: modifications and recommendations..Microsurgery1996;17:358-65

[34]

Capelouto CC,Loughlin KR.Complete phalloplasty with a prelaminated osteocutaneous fibula flap..J Urol1997;158:2238-9

[35]

Christiano JG,Rodriguez ED.Repair of recurrent cleft palate with free vastus lateralis muscle flap..Cleft Palate Craniofac J2012;49:245-8

[36]

Woerdeman LAE,Griffioen FMM.Sensate osteocutaneous fibula flap: anatomic study of the innervation pattern of the skin flap..Head Neck1998;20:310-4

[37]

Schaff J.A new protocol for complete phalloplasty with free sensate and prelaminated osteofasciocutaneous flaps: experience in 37 patients..Microsurgery2009;29:413-9

[38]

van Rooij JC.The effect of linguistic entropy on speech perception in noise in young and elderly listeners..J Acoust Soc Am1991;90:2985-91

[39]

Djordjevic ML,Vukovic PM,Perovic SV.Musculocutaneous latissimus dorsi free transfer flap for total phalloplasty in children..J Pediatr Urol2006;2:333-9

[40]

Perovic SV,Bumbasirevic M,Vukovic P.Total phalloplasty using a musculocutaneous latissimus dorsi flap..BJU Int2007;100:899-905discussion 905

[41]

Lugo-Fagundo C,O’Brien-Coon D.The role of cinematic rendering in pre-operative planning of a thoracodorsal artery perforator flap (TDAP) phalloplasty: a case study..BJR Case Rep2019;5:20180084 PMCID:PMC6726175

[42]

Djordjevic ML.Novel surgical techniques in female to male gender confirming surgery..Transl Androl Urol2018;7:628-38 PMCID:PMC6127556

[43]

Dong L,He L,Zhang Z.Penile reconstruction by preexpanded free scapular flap in severely burned patient..Ann Plast Surg.2014;73 Suppl 1:S27-30

[44]

Ranno R,Hýza P,Justan I.Neo-phalloplasty with re-innervated latissimus dorsi free flap: a functional study of a novel technique..Acta Chir Plast2007;49:3-7

[45]

Hoebeke PB,Beysens M,Lumen N.Erectile implants in female-to-male transsexuals: our experience in 129 patients..Eur Urol2010;57:334-40

[46]

Garaffa G,Ralph DJ.An update on penile reconstruction..Asian J Androl2011;13:391-4 PMCID:PMC3739352

[47]

Monstrey SJ,Hoebeke P.Sex reassignment surgery in the female-to-male transsexual..Semin Plast Surg2011;25:229-44 PMCID:PMC3312187

[48]

Sonmez E,Siemionow M.Penis allotransplantation model in the rat..Ann Plast Surg2009;62:304-10

[49]

Koga H,Wang K,Lane GJ.Experimental allogenic penile transplantation..J Pediatr Surg2003;38:1802-5

[50]

Akyurek M,Safak T,Dunn RM.The penile flap in the rat: description and autotransplantation..Ann Plast Surg2005;55:94-100discussion 101

[51]

Zhao Y,Zhang L,Wang W.Penis allotransplantation in beagle dog..Biomed Res Int2016;2016:1489204 PMCID:PMC4761661

[52]

Sopko NA,Lough DM,Harris K.Ex vivo model of human penile transplantation and rejection: implications for erectile tissue physiology..Eur Urol2017;71:584-93

[53]

van der Merwe A,Zühlke A,Zarrabi AD.Penile allotransplantation for penis amputation following ritual circumcision: a case report with 24 months of follow-up..Lancet2017;390:1038-47

[54]

Ngaage LM,Sugarman J,Cooney CM.The baltimore criteria for an ethical approach to penile transplantation: a clinical guideline..Transpl Int2020;33:471-82

[55]

Diaz-Siso JR,Plana NM,Stranix JT.Vascularized composite allotransplantation: alternatives and catch-22s..Plast Reconstr Surg2018;142:1320-6

[56]

Sixty-Third World Health Assembly, World Health OrganizationWHO Guiding Principles on Human Cell, Tissue and Organ Transplantation..Cell Tissue Bank2010;11:413-9

[57]

Marchac A,Paris J,Vazquez MP.Ethical issues in pediatric face transplantation: should we perform face transplantation in children?.Plast Reconstr Surg2016;138:449-54

[58]

Amaral S.Pediatric and congenital hand transplantation..Curr Opin Organ Transplant2017;22:477-83

[59]

Leijte JA,Antonini N,Horenblas S.Recurrence patterns of squamous cell carcinoma of the penis: recommendations for follow-up based on a two-centre analysis of 700 patients..Eur Urol2008;54:161-8

[60]

Pomahac B,Bueno EM,Levin LS.Living donation of vascularized composite allografts..Plast Reconstr Surg2018;142:405e-11

[61]

Sopko NA,Lough D,Lee WPA.Penile allotransplantation for complex genitourinary reconstruction..J Urol2017;198:274-80

PDF

212

Accesses

0

Citation

Detail

Sections
Recommended

/