Health-related Quality of Life (HRQOL) Outcomes of Selective/Nonselective Thoracic Fusion for Lenke 1C Adolescent Idiopathic Scoliosis (AIS) Patients with a Minimum 4-year Follow-up
Chuan Luo, Zhipeng Deng, Junhu Li, Zhuhai Li, Lihang Wang, Liyu Ran, Yueming Song, Shishu Huang, Lei Wang, Litai Ma
Health-related Quality of Life (HRQOL) Outcomes of Selective/Nonselective Thoracic Fusion for Lenke 1C Adolescent Idiopathic Scoliosis (AIS) Patients with a Minimum 4-year Follow-up
Objective:: Both the selective thoracic fusion (STF) and nonselective thoracic fusion (NSTF) are treatments for Lenke 1C adolescent idiopathic scoliosis (AIS). To date, the impacts of the two surgical strategies on patients' long-term quality of life remain unclear. Therefore, the purpose of this study was to explore the long-term effects of STF/NSTF on the quality of life in Lenke 1C AIS patients through a 4–10-year follow-up.
Methods:: From January 2011 to April 2018, according to the inclusion and exclusion criteria, a retrospective single-center study of 75 surgical patients with Lenke 1C curves was performed (n = 75). They all underwent posterior fusion, and patients were divided into the selective thoracic fusion (STF) group (n = 42) and the nonselective thoracic fusion (NSTF) group (n = 33) based on their surgical approach. All participants received the survey of the visual analogue scale (VAS), SRS30, SF12, and Oswestry disability index (ODI) scales. Patients' gender, age, body mass index (BMI), surgical approach (STF/NSTF), surgical segments (UIV and LIV), follow-up time, complications, preoperative, postoperative, and last follow-up Cobb angles, and health-related quality of life (HRQOL) outcomes were collected, and analyzed through the Shapiro-Wilks test, Wilcoxon rank-sum test, t-test, and χ2 test.
Results:: The mean follow-up of the entire cohort was 73 ± 5.6 months. The lumbar Cobb angle in the STF group improved from 31.8 ± 6.5° to 11.5 ± 5.1° after the operation and 10.3 ± 6.9° at the last follow-up. The postoperative correction rate of the lumbar curve was 63.8%, which increased to 67.7% at the last follow-up. In the NSTF group, the lumbar Cobb angle improved from 34.3 ± 11.3° to 4.3 ± 3.7° after the operation, and was 5.1 ± 3.1° at the last follow-up. The postoperative correction rate of the lumbar curve was 87.4%, and 85.1% at the last follow-up. At the last follow-up, the STF group had higher overall HRQOL scores than the NSTF group, and there were statistically differences between the different groups (STF/NSTF) in SRS-30-Mental health (p = 0.03), SRS-30-Satisfaction with management (p = 0.02), SRS-30-Pain (p = 0.03), ODI (p = 0.01), SF-12 PCS (p = 0.03), VAS back pain (p = 0.005) and VAS leg pain (p = 0.001). No statistically differences were found in SF12 MCS, SRS-30-Self-image/Appearance and SRS-30 Function/activity.
Conclusion:: After 4–10 years of follow-up, we found that the STF group achieved satisfactory correction results, and compared with the NSTF group, their overall HRQOL scores were higher, especially in terms of pain and satisfaction, where the STF group shows a significant advantage.
Adolescent scoliosis / Health-related quality of life / Selective thoracic fusion
[1] |
Weinstein SL, Dolan LA, Cheng JC, Danielsson A, Morcuende JA. Adolescent idiopathic scoliosis. Lancet. 2008;371:1527–1537.
|
[2] |
Sun X, Wang B, Qiu Y, Zhu ZZ, Zhu F, Yu Y, et al. Outcomes and predictors of brace treatment for girls with adolescent idiopathic scoliosis. Orthop Surg. 2010;2:285–290.
|
[3] |
Tambe AD, Panikkar SJ, Millner PA, Tsirikos AI. Current concepts in the surgical management of adolescent idiopathic scoliosis. Bone Joint J. 2018;100-B:415–424.
|
[4] |
Fu J, Liu C, Zhang YG, Zheng GQ, Zhang GY, Song K, et al. Three-dimensional computed tomography for assessing lung morphology in adolescent idiopathic scoliosis following posterior spinal fusion surgery. Orthop Surg. 2015;7:43–49.
|
[5] |
Lenke LG, Betz RR, Harms J, Bridwell KH, Clements DH, Lowe TG, et al. Adolescent idiopathic scoliosis: a new classification to determine extent of spinal arthrodesis. J Bone Joint Surg Am. 2001;83:1169–1181.
|
[6] |
He Z, Qin XD, Chen XP, et al. Posterior fusion strategy of lowest instrumented vertebra at the apical vertebra of the lumbar curve in Lenke type C ad⁃olescent idiopathic scoliosis. Chin J Orthop. 2022;42:10.
|
[7] |
Schulz J, Asghar J, Bastrom T, Shufflebarger H, Newton PO, Sturm P, et al. Optimal radiographical criteria after selective thoracic fusion for patients with adolescent idiopathic scoliosis with a C lumbar modifier: does adherence to current guidelines predict success? Spine (Phila Pa 1976). 2014;39:E1368–E1373.
|
[8] |
Kwan MK, Chiu CK, Tan PH, Chian XH, Ler XY, Ng YH, et al. Radiological and clinical outcome of selective thoracic fusion for patients with Lenke 1C and 2C adolescent idiopathic scoliosis with a minimum follow-up of 2 years. Spine J. 2018;18:2239–2246.
|
[9] |
Wang Y, Bunger CE, Zhang Y, et al. Extensive fusion for Lenke 3C and 6C scoliosis: a two year radiographic follow-up. Int Orthop. 2012;36:795–801.
|
[10] |
Chang DG, Yang JH, Suk SI, Suh S-W, Kim Y-H, Cho W, et al. Importance of distal fusion level in major thoracolumbar and lumbar adolescent idiopathic scoliosis treated by rod derotation and direct vertebral rotation following pedicle screw instrumentation. Spine (Phila Pa 1976). 2017;42:E890–E898.
|
[11] |
Fischer CR, Kim Y. Selective fusion for adolescent idiopathic scoliosis: a review of current operative strategy. Eur Spine J. 2011;20:1048–1057.
|
[12] |
Begum MR, Hossain MA. Validity and reliability of visual analogue scale (VAS) for pain measurement. J Med Case Rep. 2019;2:394–402.
|
[13] |
Brodke DS, Goz V, Lawrence BD, Spiker WR, Neese A, Hung M. Oswestry disability index: a psychometric analysis with 1,610 patients. Spine J. 2017;17:321–327.
|
[14] |
Ryu S, Pugh SL, Gerszten PC, Yin FF, Timmerman RD, Hitchcock YJ, et al. RTOG 0631 phase 2/3 study of image guided stereotactic radiosurgery for localized (1-3) spine metastases: phase 2 results. Pract Radiat Oncol. 2014;4:76–81.
|
[15] |
Kyrölä K, Järvenpää S, Ylinen J, Mecklin JP, Repo JP, Häkkinen A. Reliability and validity study of the Finnish adaptation of Scoliosis Research Society questionnaire version SRS-30. Spine. 2017;42:943–949.
|
[16] |
Rojc M, Sršen KG, Mohar J, Vidmar G. Slovenian version of the scoliosis research society instrument-22 revised (SRS-22r) in adolescents and adults: psychometric properties and some implications. J Pediatr Rehabil Med. 2023;16:1–9.
|
[17] |
Chang KW, Leng X, Zhao W, Chen YY, Chen TC, Chang KI. Broader curve criteria for selective thoracic fusion. Spine (Phila Pa 1976). 2011;36:1658–1664.
|
[18] |
Trobisch PD, Ducoffe AR, Lonner BS, Errico TJ. Choosing fusion levels in adolescent idiopathic scoliosis. J Am Acad Orthop Surg. 2013;21:519–528.
|
[19] |
Collins SL, Moore AR, McQuay HJ. The visual analogue pain intensity scale: what is moderate pain in millimetres? Pain. 1997;72:95–97.
|
[20] |
Hjermstad MJ, Fayers PM, Haugen DF, Caraceni A, Hanks GW, Loge JH, et al. Studies comparing numerical rating scales, verbal rating scales, and visual analogue scales for assessment of pain intensity in adults: a systematic literature review. J Pain Symptom Manage. 2011;41:1073–1093.
|
[21] |
Williams ACC, Davies HTO, Chadury Y. Simple pain rating scales hide complex idiosyncratic meanings. Pain. 2000;85:457–463.
|
[22] |
Herdea A, Stancu TA, Ulici A, Lungu CN, Dragomirescu M-C, Charkaoui A. Quality of life evaluation using SRS-30 score for operated children and adolescent idiopathic scoliosis. Medicina (Kaunas). 2022;58:674.
|
[23] |
Kyrola K, Jarvenpaa S, Ylinen J, Mecklin J, Repo JP, Häkkinen A. Reliability and validity study of the Finnish adaptation of scoliosis research society questionnaire version SRS-30. Spine (Phila Pa 1976). 2017;42:943–949.
|
[24] |
Windsor TD, Rodgers B, Butterworth P, Anstey KJ, Jorm AF. Measuring physical and mental health using the SF-12: implications for community surveys of mental health. Aust N Z J Psychiatry. 2006;40:797–803.
|
[25] |
Ware J, Kosinski M, Keller SD. A 12-item short-form health survey: construction of scales and preliminary tests of reliability and validity. Med Care. 1996;34:220–233.
|
[26] |
Hagell P, Westergren A, Arestedt K. Beware of the origin of numbers: standard scoring of the SF-12 and SF-36 summary measures distorts measurement and score interpretations. Res Nurs Health. 2017;40:378–386.
|
[27] |
Duramaz A, Karaali E, Ozturk V, Ziroğlu N, İlter MH, Bayrak A. Importance of lowest instrumented vertebra on clinical and radiological outcomes in patients with Lenke type 3C adolescent idiopathic scoliosis: a minimum 4-year follow-up. J Pediatr Orthop B. 2020;29:580–589.
|
[28] |
Fairbank JC, Pynsent PB. The Oswestry disability index. Spine (Phila Pa 1976). 2000;25:2940–2952. discussion 2952.
|
[29] |
Moe JH. A critical analysis of methods of fusion for scoliosis; an evaluation in two hundred and sixty-six patients. J Bone Joint Surg Am. 1958;40-A:529–554. passim, 697.
|
[30] |
King HA, Moe JH, Bradford DS, Winter RB. The selection of fusion levels in thoracic idiopathic scoliosis. J Bone Joint Surg Am. 1983;65:1302–1313.
|
[31] |
Crawford CH, Lenke LG, Sucato DJ, Stephens Richards B, Emans JB, Vitale MG, et al. Selective thoracic fusion in Lenke 1C curves: prevalence and criteria. Spine (Phila Pa 1976). 2013;38:1380–1385.
|
[32] |
Marie-Hardy L, Besse M, Chatelain L, Pannier S, Glorion C, Ferrero E. Does the distal level really matter in the setting of health-related quality of life? Assessment of a series of adolescent idiopathic scoliosis patients at more than 7 years following surgery. Spine. 2022;47:E545–E550.
|
[33] |
Kelly AM. Does the clinically significant difference in visual analog scale pain scores vary with gender, age, or cause of pain? Acad Emerg Med. 1998;5:1086–1090.
|
[34] |
Larson AN, Fletcher ND, Daniel C, Richards BS. Lumbar curve is stable after selective thoracic fusion for adolescent idiopathic scoliosis: a 20-year follow-up. Spine (Phila Pa 1976). 2012;37:833–839.
|
[35] |
Boniello AJ, Hasan S, Yang S, Jalai CM, Worley N, Passias PG. Selective versus nonselective thoracic fusion in Lenke 1C curves: a meta-analysis of baseline characteristics and postoperative outcomes. J Neurosurg Spine. 2015;23:721–730.
|
[36] |
Louer C, Yaszay B, Cross M, Bartley CE, Bastrom TP, Shah SA, et al. Ten-year outcomes of selective fusions for adolescent idiopathic scoliosis. J Bone Joint Surg Am. 2019;101:761–770.
|
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