Androgen-type 2 innate lymphoid cells-dendritic cell axis modulates sex-associated differences in skin immune responses

Shi-Jun He; Jian-Ping Zuo; Ze-Min Lin

doi:10.1002/mco2.732

MedComm ›› 2024, Vol. 5 ›› Issue (10) :e732 DOI: 10.1002/mco2.732

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Androgen-type 2 innate lymphoid cells-dendritic cell axis modulates sex-associated differences in skin immune responses

Shi-Jun He ¹^,²^,^†
, Jian-Ping Zuo ²^,³
, Ze-Min Lin ²^,³^,^†

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Shi-Jun He, Jian-Ping Zuo, Ze-Min Lin. Androgen-type 2 innate lymphoid cells-dendritic cell axis modulates sex-associated differences in skin immune responses. MedComm, 2024, 5(10): e732 DOI:10.1002/mco2.732

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References

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[1]	Chi L, Liu C, Gribonika I, et al. Sexual dimorphism in skin immunity is mediated by an androgen-ILC2-dendritic cell axis. Science. 2024; 384(6692): eadk6200.

[2]	Laffont S, Blanquart E, Savignac M, et al. Androgen signaling negatively controls group 2 innate lymphoid cells. J Exp Med. 2017; 214(6): 1581-1592.

[3]	Hoffmann JP, Liu JA, Seddu K, Klein SL. Sex hormone signaling and regulation of immune function. Immunity. 2023; 56(11): 2472-2491.

[4]	He S-J, Yang F, Zuo J-P, Lin Z-M. Fine-tuning immunity against cancer: the emergence of engineered commensal microbiota. Sci Bull. 2023; 68(12): 1235-1237.

[5]	Pace F, Watnick PI. The interplay of sex steroids, the immune response, and the intestinal microbiota. Trends Microbiol. 2021; 29(9): 849-859.

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2024 The Author(s). MedComm published by Sichuan International Medical Exchange & Promotion Association (SCIMEA) and John Wiley & Sons Australia, Ltd.