Enhancing the effectiveness of anti-respiratory virus vaccines by bolstering mucosal immunity and cellular defenses

Rubing Xue; Sijia Liu; Fangfang Zhou

doi:10.1002/mco2.616

MedComm ›› 2024, Vol. 5 ›› Issue (9) :e616 DOI: 10.1002/mco2.616

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Enhancing the effectiveness of anti-respiratory virus vaccines by bolstering mucosal immunity and cellular defenses

Rubing Xue ¹^,²
, Sijia Liu ³^,^†
, Fangfang Zhou ¹^,^†

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Rubing Xue, Sijia Liu, Fangfang Zhou. Enhancing the effectiveness of anti-respiratory virus vaccines by bolstering mucosal immunity and cellular defenses. MedComm, 2024, 5(9): e616 DOI:10.1002/mco2.616

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References

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[2]	McMahan K, Wegmann F, Aid M, et al. Mucosal boosting enhances vaccine protection against SARS-CoV-2 in macaques. Nature. 2024; 626(7998): 385-391.

[3]	He X, Aid M, Chandrashekar A, et al. A homologous or variant booster vaccine after Ad26.COV2.S immunization enhances SARS-CoV-2-specific immune responses in rhesus macaques. Sci Transl Med. 2022; 14(638): eabm4996.

[4]	Uddbäck I, Michalets SE, Saha A, et al. Prevention of respiratory virus transmission by resident memory CD8+ T cells. Nature. 2024; 626(7998): 392-400.

[5]	McMaster SR, Wilson JJ, Wang H, Kohlmeier JE. Airway-resident memory CD8 T cells provide antigen-specific protection against respiratory virus challenge through rapid IFN-γ production. J Immunol. 2015; 195(1): 203-209.

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2024 The Author(s). MedComm published by Sichuan International Medical Exchange & Promotion Association (SCIMEA) and John Wiley & Sons Australia, Ltd.