The presence of Y chromosome leads to the difference of cancer in patients with different sexes

Yingqi Kuang; Wenhuan Sun; Long Zhang

doi:10.1002/mco2.468

MedComm ›› 2024, Vol. 5 ›› Issue (1) :e468 DOI: 10.1002/mco2.468

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The presence of Y chromosome leads to the difference of cancer in patients with different sexes

Yingqi Kuang ¹^,²
, Wenhuan Sun ²
, Long Zhang ¹^,³^,^†

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cancer / sex / Y chromosome

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Yingqi Kuang, Wenhuan Sun, Long Zhang. The presence of Y chromosome leads to the difference of cancer in patients with different sexes. MedComm, 2024, 5(1): e468 DOI:10.1002/mco2.468

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References

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[2]	Li JX, Lan ZD, Liao WT, et al. Histone demethylase KDM5D upregulation drives sex differences in colon cancer. Nature. 2023:632-639.

[3]	Haupt S, Caramia F, Klein SL, Rubin JB, Haupt Y. Sex disparities matter in cancer development and therapy. Nat Rev Cancer. 2021;21(6):393-407.

[4]	Scott AC, Dündar F, Zumbo P, et al. TOX is a critical regulator of tumour-specific T cell differentiation. Nature. 2019;571(7764):270-274.

[5]	Yi CL, Troutman S, Fera D, et al. A tight junction-associated Merlin-angiomotin complex mediates Merlin's regulation of mitogenic signaling and tumor suppressive functions. Cancer Cell. 2011;19(4):527-540.