Thirty years of the human immunodeficiency virus epidemic and beyond
Fariba S Younai
International Journal of Oral Science ›› 2013, Vol. 5 ›› Issue (4) : 191 -199.
Expanded preventative and therapeutic efforts will be critical to maintaining the momentum in the fight against human immunodeficiency virus (HIV), concludes Fariba Younai of the University of California at Los Angeles, USA. Younai has reviewed the scientific and medical advances that help HIV patients in controlling their disease, as well as assist patients and health-care workers in containing the spread of this virus. She noted that existing treatments control but do not eliminate infection. Younai also listed causes for concern, including high disease burdens and mortality rates in the developing world. She explored the value of preventative strategies, such as drug prophylaxis to prevent HIV transmission by pregnant mothers to their children, and male circumcision. She also examined experimental efforts to eradicate latent viral reservoirs that might eventually give rise to AIDS.
human immunodeficiency virus / treatment / prevention / global impact / antiretrovirals / epidemiology
| [1] |
Centers for Disease Control Kaposi’s sarcoma Pneumocystis pneumonia among homosexual men—New York City and California. Morbid Mortal Wkly Rep, 1981, 30(25): 305-308. |
| [2] |
|
| [3] |
Centers for Disease Control Pneumocystis carinii pneumonia among persons with hemophilia A. Morbid Mortal Wkly Rep, 1982, 31(27): 365-367. |
| [4] |
Centers for Disease Control Update on acquired immune deficiency syndrome (AIDS) among patients with hemophilia A. Morbid Mortal Wkly Rep, 1982, 31(48): 644-646. |
| [5] |
Centers for Disease Control Update on acquired immune deficiency syndrome (AIDS) among patients with hemophilia A. Morbid Mortal Wkly Rep, 1982, 31(48): 652. |
| [6] |
Centers for Disease Control Possible transfusion-associated acquired immune deficiency syndrome (AIDS)—California. Morbid Mortal Wkly Rep, 1982, 31(48): 652-654. |
| [7] |
Centers for Disease Control Update on acquired immune deficiency syndrome (AIDS)—United States. Morbid Mortal Wkly Rep, 1982, 31(37): 507-508. |
| [8] |
Centers for Disease Control Immunodeficiency among female sexual partners of males with acquired immune deficiency syndrome (AIDS)—New York. Morbid Mortal Wkly Rep, 1983, 31(52): 697-698. |
| [9] |
|
| [10] |
|
| [11] |
|
| [12] |
|
| [13] |
|
| [14] |
|
| [15] |
|
| [16] |
|
| [17] |
|
| [18] |
|
| [19] |
|
| [20] |
UNAIDS. World AIDS day report 2011. Geneva: UNAIDS. Available at http://www.unaids.org/en/media/unaids/contentassets/documents/unaidspublication/2011/jc2216_worldaidsday_report_2011_en.pdf (accessed 5 December 2012). |
| [21] |
UNAIDS. AIDS epidemic update. Joint United Nations Programme on HIV/AIDS (UNAIDS) and World Health Organization (WHO) 2009. UNAIDS/09.36E/JC1700E, November 2009. Geneva: UNAIDS. Available at http://data.unaids.org/pub/Report/2009/JC1700_Epi_Update_2009_en.pdf (accessed 5 December 2012). |
| [22] |
|
| [23] |
|
| [24] |
|
| [25] |
|
| [26] |
|
| [27] |
|
| [28] |
|
| [29] |
|
| [30] |
|
| [31] |
|
| [32] |
|
| [33] |
|
| [34] |
|
| [35] |
|
| [36] |
|
| [37] |
|
| [38] |
|
| [39] |
|
| [40] |
International HIV Controllers Study |
| [41] |
|
| [42] |
|
| [43] |
|
| [44] |
|
| [45] |
US Food and Drug Administration. Antiretroviral drugs used in the treatment of HIV infection. Silver Spring: US FDA. Available at http://www.fda.gov/ForConsumers/byAudience/ForPatientAdvocates/HIVandAIDSActivities/ucm118915.htm (accessed 5 December 2012). |
| [46] |
|
| [47] |
AIDS Info. Guidelines for the use of antiretroviral agents in HIV-1-infected adults and adolescents. Rockville: AIDS Info. Available at http://aidsinfo.nih.gov/guidelines (accessed 12 July 2012). |
| [48] |
|
| [49] |
|
| [50] |
|
| [51] |
|
| [52] |
|
| [53] |
Division of Global HIV/AIDS, Center for Global Health Integrated prevention services for HIV infection, viral hepatitis, sexually transmitted diseases, and tuberculosis for persons who use drugs illicitly: summary guidance from CDC and the U.S. Department of Health and Human Services. MMWR Recomm Rep, 2012, 61(RR-5): 1-40. |
| [54] |
|
| [55] |
|
| [56] |
|
| [57] |
|
| [58] |
|
| [59] |
|
| [60] |
|
| [61] |
|
| [62] |
|
| [63] |
DAD Study Group |
| [64] |
|
| [65] |
|
| [66] |
|
| [67] |
|
| [68] |
|
| [69] |
Office of National AIDS Policy. National HIV/AIDS Strategy for the United States. Washington: Office of National AIDS Policy, 2010. Available at http://www.whitehouse.gov/administration/eop/onap/nhas (accessed 5 December 2012). |
| [70] |
|
| [71] |
World Health Organization. New guidance on prevention of mother-to-child transmission of HIV and infant feeding in the context of HIV, 2010. Geneva: World Health Organization. Available at http://www.who.int/hiv/pub/mtct/PMTCTfactsheet/en/index.html (accessed 12 December 2012). |
| [72] |
UNAIDS. Countdown to zero: global plan towards the elimination of new HIV infections among children by 2015 and keeping their mothers alive. Geneva: UNAIDS, 2011. Available at http://www.unaids.org/en/media/unaids/contentassets/documents/unaidspublication/2011/20110609_JC2137_Global-Plan-Elimination-HIV-Children_en.pdf (accessed 10 December 2012). |
| [73] |
|
| [74] |
|
| [75] |
Government of Kenya. Kenya AIDS Indicator Survey 2007. Nairobi: Government of Kenya, 2009, Available at http://nascop.or.ke/library/3d/Official_KAIS_Report_20091.pdf (accessed 17 December 2012). |
| [76] |
Centers for Disease Control and Prevention. Diagnoses of HIV infection and AIDS in the United States and Dependent Areas, 2010. HIV Surveillance Report, Volume 22. Atlanta: CDC. Available at http://www.cdc.gov/hiv/surveillance/resources/reports/2010report/index.htm (accessed 5 December 2012). |
| [77] |
CDC Antiretroviral postexposure prophylaxis after sexual, injection-drug use, or other nonoccupational exposure to HIV in the United States. Morbid Mortal Wkly Rep, 2005, 54(RR-02): 1-20. |
| [78] |
CDC Interim guidance: preexposure prophylaxis for prevention of HIV infection in men who have sex with men and women. Morbid Mortal Wkly Rep, 2011, 60(3): 65-68. |
| [79] |
CDC Interim Guidance for clinicians considering the use of preexposure prophylaxis for the prevention of HIV infection in heterosexually active adults. Morbid Mortal Wkly Rep, 2012, 61(31): 586-589. |
| [80] |
Botswana Harvard AIDS Institute. Botswana Harvard AIDS Institute Partnership: Mochudi Prevention Project. Gaborone: Botswana Harvard AIDS Institute, 2011. Available at http://www.hsph.harvard.edu/bhp/research/hiv_prevention/mochudi_prevention.html (accessed 3 July 2012). |
| [81] |
AIDS HIV Prevention Trial Network. HTPN 071, population effects of antiretroviral therapy to reduce HIV transmission (PopART): a cluster randomized trial of the impact of a combination prevention package on population-level HIV incidence in Zambia and South Africa. Available at http://www.hptn.org/research_studies/hptn071.asp (accessed 3 July 2013). |
| [82] |
Walensky RP . Combination HIV prevention: the value and interpretation of mathematical models. Curr HIV/AIDS Rep 2013; [Epub ahead of print]. |
| [83] |
|
| [84] |
|
| [85] |
|
| [86] |
|
| [87] |
|
| [88] |
Monogram Biosciences. Trofile TM – Monogram’s co-receptor tropism assay. San Francisco: Monogram Biosciences. Available at http://www.monogrambio.com/414.aspx. (accessed 21 December 2012). |
| [89] |
|
| [90] |
|
| [91] |
|
| [92] |
|
| [93] |
|
| [94] |
|
| [95] |
|
| [96] |
|
| [97] |
|
| [98] |
|
| [99] |
|
| [100] |
|
| [101] |
|
| [102] |
|
| [103] |
|
| [104] |
|
| [105] |
|
| [106] |
|
| [107] |
|
| [108] |
|
| [109] |
|
| [110] |
|
| [111] |
|
| [112] |
|
| [113] |
|
| [114] |
The rgp120 HIV Vaccine Study Group Placebo-controlled phase 3 trial of a recombinant glycoprotein 120 vaccine to prevent HIV-1 infection. J Infect Dis, 2005, 191(5): 654-665. |
| [115] |
Fauci AS . The release of new data from the HVTN 502 (STEP) HIV vaccine study. NIH News 2007. Available at http://www3.niaid.nih.gov/about/directors/news/step11707.htm (accessed 17 December 2012). |
| [116] |
|
| [117] |
|
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