Contemporary understanding of the risk factors for chronic kidney disease in cold area

Xinrui Wei, Yongchen Wang

PDF(478 KB)
PDF(478 KB)
Frigid Zone Medicine ›› 2022, Vol. 2 ›› Issue (4) : 204-213.
REVIEW

Contemporary understanding of the risk factors for chronic kidney disease in cold area

Author information +
History +

Abstract

The management of chronic kidney disease (CKD) patients in cold areas is an important task in the daily practice of primary medical and health institutions. An important way to reduce the burden of CKD is to achieve early identification of and implement timely intervention on the relevant risk factors. Studies have shown that diet, alcohol, tobacco, air, sedentary and other factors in cold areas have negative impacts on human kidneys; yet, our current understanding of the effect of cold stimulation on CKD remains blurry. This paper introduces the research progress of risk factors related to CKD in cold areas and analytically summarizes the pathogenesis of CKD caused by cold stimulation, aiming to provide a reference work for the prevention, screening, evaluation, and management of CKD in cold areas.

Keywords

chronic kidney disease / cold areas / eating habits / lifestyle / cold stimulation

Cite this article

Download citation ▾
Xinrui Wei, Yongchen Wang. Contemporary understanding of the risk factors for chronic kidney disease in cold area. Frigid Zone Medicine, 2022, 2(4): 204‒213

References

[[1]]
GBD Chronic Kidney Disease Collaboration. Global, regional, and national burden of chronic kidney disease, 1990-2017: a systematic analysis for the global burden of disease study 2017. Lancet, 2020; 395(10225): 709-733.
[[2]]
Bello A, Levin A, Tonelli M, et al. Global Kidney Health Atlas:A report by the international society of nephrology on the current state of organization and structures for kidney care across the Globe, Brussels, Belgium: International Society of Nephrology, 2019.
[[3]]
Song X, Wang S, Hu Y, et al. Impact of ambient temperature on morbidity and mortality: An overview of reviews. Sci Total Environ, 2017; 586: 241-254.
[[4]]
Wang F, He K, Wang J, et al. Prevalence and risk factors for CKD: A comparison between the adult populations in China and the United States. Kidney Int Rep, 2018; 3(5): 1135-1143.
[[5]]
Zhang L, Zhao M H, Zuo L, et al. China Kidney Disease Network (CK-NET) 2016 annual data report. Kidney Int Suppl (2011), 2020; 10(2): e97-e185.
[[6]]
National Bureau of Statistics of China. China Statistics Yearbook 2016. Beijing: China Statistics Press, 2017.
[[7]]
Jiang R, Zhao Y, Wang Y. Discussion on the model of community management of chronic diseases in cold areas. Frigid Zone Medicine, 2020; 1(1): 17-22.
[[8]]
GBD 2019 Risk Factors Collaborators. Global burden of 87 risk factors in 204 countries and territories, 1990-2019: a systematic analysis for the Global Burden of Disease Study. Global Health Metrics, 2020; 396(10258): 1223-1249.
[[9]]
Song J, Qin W, Wang R, et al. A global comprehensive analysis of ambient low temperature and non-communicable diseases burden during 1990-2019. Environ Sci Pollut Res Int, 2022; 29(44): 66136-66147.
[[10]]
Gouda H N, Charlson F sorsdahl K, et al. Burden of non-communicable diseases in sub-Saharan Africa, 1990-2017: results from the Global Burden of Disease Study. Lancet Glob Health, 2019; 7(10): e1375-e1387.
[[11]]
UNAIDS. Full Report — In Danger:UNAIDS Global AIDS Update 2022. Geneva, Switzerland: Global Data on HIV Epidemiology and Response, 2022.
[[12]]
Wyatt C, Meliambro K, Klotman P. Recent Progress in HIV-associated nephropathy. Annul Rev Med, 2012; 63: 1-13.
[[13]]
Bundhamcharoen K, Odton P, Phulkerd S, et al. Burden of disease in Thailand: changes in health gap between 1999 and 2004. BMC Public Health, 2011; 11: 53.
[[14]]
Chen R, Kang E, Ji X, et al. Cold regions in China. Cold Regions Science and Technology, 2006; 45(2): 95-102.
[[15]]
Zhang L, Wang F, Wang L, et al. Prevalence of chronic kidney disease in China: a cross-sectional survey. Lancet, 2012; 379(9818): 815-822.
[[16]]
McCormack M C, Paulin L M, Gummerson C E, et al. Colder temperature is associated with increased COPD morbidity. Eur Respir J, 2017; 49(6): 1601501.
[[17]]
Wang X, Jiang Y, Bai Y, et al. Association between air temperature and the incidence of acute coronary heart disease in Northeast China. Clin Interv Aging, 2020; 15: 47-52.
[[18]]
Vallianou N G, Geladari E V, Kounatidis D, et al. Diabetes mellitus in the era of climate change. Diabetes Metab, 2021; 47(4): 101205.
[[19]]
Phanprasit W, Chotiphan C, Auttanate N, et al. Cold-related pain in the face, upper limbs, and lower body among thai chicken industry workers: a cross-sectional study. Int. Arch. Occup. Environ. Health, 2021; 94(5): 799-812.
[[20]]
Patten S B, Williams J V, Lavorato D H, et al. Major depression prevalence increases with latitude in Canada. Can J Psychiatry, 2017; 62(1): 62-66.
[[21]]
Wang J, Lin X, Bloomgarden Z T, et al. The Jiangnan diet, a healthy diet pattern for Chinese. J Diabetes, 2020; 12(5): 365-371.
[[22]]
Wang X, Liu A, Du M, et al. Diet quality is associated with reduced risk of hypertension among Inner Mongolia adults in northern China. Public Health Nutr, 2020; 23(9): 1543-1554.
[[23]]
Cao Y J, Wang H J, Zhang B, et al. Associations of fat and carbohydrate intake with becoming overweight and obese: an 11-year longitudinal cohort study. Br J Nutr, 2020; 124(7): 715-728.
[[24]]
Htet A S, Kjøllesdal M K, Aung W P, et al. Lipid profiles and determinants of total cholesterol and hypercholesterolemia among 25- 74 years old urban and rural citizens of the Yangon Region, Myanmar: a cross-sectional study. BMJ Open, 2017; 7(11): e017465.
[[25]]
Saravanan S, Pari L. Protective effect of thymol on high fat diet induced diabetic nephropathy in C57BL/6J mice. Chem Biol Interact, 2016; 245: 1-11.
[[26]]
Xi Y, Niu L, Cao N, et al. Prevalence of dyslipidemia and associated risk factors among adults aged ≥35 years in northern China: a cross-sectional study. BMC Public Health, 2020; 20(1): 1068.
[[27]]
Karpov Y, Khomitskaya Y. Prometheus: an observational, cross-sectional, retrospective study of hypertriglyceridemia in Russia. Cardiovasc Diabetol, 2015; 14: 115.
[[28]]
Moorhead J F, Chan M K, El-Nahas M, et al. Lipid nephrotoxicity in chronic progressive glomerular and tubulo-interstitial disease. Lancet, 1982; 2(8311): 1309-1311.
[[29]]
Ruan X Z, Varghese Z, Moorhead JF. An update on the lipid nephrotoxicity hypothesis. Nat Rev Nephrol. 2009; 5(12): 713-721.
[[30]]
Cabandugama P K, Gardner M J, Sowers J R. The renin angiotensin aldosterone system in obesity and hypertension: roles in the cardiorenal metabolic syndrome. Med Clin North Am,2017: 101; 129-137.
[[31]]
Panizo S, Martínez-Arias L, Alonso-Montes C, et al. Fibrosis in chronic kidney disease: pathogenesis and consequences. Int J Mol Sci, 2021; 22(1): 408.
[[32]]
Culver S, Li C, Siragy H M. Intrarenal angiotensin-converting enzyme: the old and the new. Curr Hypertens Rep, 2017; 19(10): 80.
[[33]]
Tagawa A, Yasuda M, Kume S, et al. Impaired podocyte autophagy exacerbates proteinuria in diabetic nephropathy. Diabetes, 2016; 65(3): 755-767.
[[34]]
Weisinger J R, Kempson R L, Eldridge F L, et al. The nephrotic syndrome: a complication of massive obesity. Ann Intern Med, 1974; 81(4): 440-447.
[[35]]
Piperidou A, Loutradis C, Sarafidis P. SGLT-2 inhibitors and nephroprotection: current evidence and future perspectives. J Hum Hypertens, 2021; 35(1): 12-25.
[[36]]
Fu E L, Evans M, Clase C M, et al. Stopping renin-angiotensin system inhibitors in patients with advanced CKD and risk of adverse outcomes: a nationwide study. J Am Soc Nephrol, 2021; 32(2): 424-435.
[[37]]
Rodrigues J C, Haas M, Reich H N. IgA nephropathy. Clin J Am Soc Nephrol, 2017; 12(4): 677-686.
[[38]]
Zheng Z G, Zhu S T, Cheng H M, et al. Discovery of a potent SCAP degrader that ameliorates HFD-induced obesity, hyperlipidemia and insulin resistance via an autophagy-independent lysosomal pathway. Autophagy, 2021; 17(7): 1592-1613.
[[39]]
Kuwahara S, Hosojima M, Kaneko R, et al. megalin-mediated tubuloglomerular alterations in high-fat diet-induced kidney disease. J Am Soc Nephrol, 2016; 27(7): 1996-2008.
[[40]]
Chen W H, Cao B, Yan J F. Transmembrane protein 126B protects against high fat diet (HFD)-induced renal injury by suppressing dyslipidemia via inhibition of ROS. Biochem Biophys Res Commun. 2019; 509(1): 40-47.
[[41]]
WHO. Guideline: Sodium intake for adults and children. World Health Organization (WHO), 2012.
[[42]]
Powles J, Fahimi S, Micha R, et al. Global, regional, and national sodium intakes in 1990 and 2010: a systematic analysis of 24h urinary sodium excretion and dietary surveys worldwide. BMJ Open, 2013; 3(12): e003733.
[[43]]
Meyer H E, Johansson L, Eggen A, et al. Salt intake assessed by 24-hour urine excretion in the Tromso Study 2015-2016. Eur. J. Prev. Cardiol, 2017; 24: S12.
[[44]]
Chen S L, Dahl C, Meyer H E, et al. Estimation of salt intake assessed by 24-hour urinary sodium excretion among somali adults in Oslo, Norway. Nutrients, 2018; 10(7): 900.
[[45]]
Wei W. Studies have again shown that salt intake in China is high. The food industry, 2019, 19(7): 152.
[[46]]
Saeki K, Obayashi K, Tone N, et al. Daytime cold exposure, and salt intake based on nocturnal urinary sodium excretion: A cross-sectional analysis of the HEIJO-KYO study. Physiol Behav, 2015; 152(Pt A): 300-306.
[[47]]
Liedtke W B, McKinley M J, Walker L L, et al. Relation of addiction genes to hypothalamic gene changes subserving genesis and gratification of a classic instinct, sodium appetite. Proc Natl Acad Sci U S A, 2011; 108(30): 12509-12514.
[[48]]
Kang M, Kang E, Ryu H, et al. Measured sodium excretion is associated with CKD progression: results from the KNOW-CKD study. Nephrol Dial Transplant, 2021; 36(3): 512-519.
[[49]]
Weinberger M H, Miller J Z, Luft F C, et al. Definitions and characteristics of sodium sensitivity and blood pressure resistance. Hypertension, 1986; 8(6 Pt 2): 127- 134.
[[50]]
Parfrey P S, Markandu N D, Roulston J E, et al. Relation between arterial pressure, dietary sodium intake, and renin system in essential hypertension. Br Med J (Clin Res Ed), 1981; 283:94-97.
[[51]]
Cao W, Li A, Wang L, et al. A salt-induced reno-cerebral reflex activates renin-angiotensin systems and promotes CKD progression. J Am Soc Nephrol, 2015; 26(7): 1619-1633.
[[52]]
Ayuzawa N, Fujita T. The mineralocorticoid receptor in salt-sensitive hypertension and renal injury. J Am Soc Nephrol, 2021; 32(2): 279-289.
[[53]]
Fenton R A, Flynn A, Shodeinde A, et al. Renal phenotype of UT-A urea transporter knockoutmice. J Am Soc Nephrol, 2005; 16: 1583-92.
[[54]]
Lemetais G, Melander O, Vecchio M, et al. Effect of increased water intake on plasma copeptin in healthy adults. Eur. J. Nutr, 2017, 57(5): 1883-1890.
[[55]]
Kanbay M, Yilmaz S, Dincer N, et al. Antidiuretic hormone and serum osmolarity physiology and related outcomes: what is old, what is new, and what is unknown? J Clin Endocrinol Metab, 2019; 104(11): 5406-5420.
[[56]]
Kitiyakara C, Chabrashvili T, Chen Y, et al. Salt intake, oxidative stress, and renal expression of NADPH oxidase and superoxide dismutase. J Am Soc Nephrol, 2003; 14(11): 2775-2782.
[[57]]
Feng W, Ying W Z, Aaron K J, et al. Transforming growth factor-β mediates endothelial dysfunction in rats during high salt intake. Am J Physiol Renal Physiol, 2015; 309(12): F1018-F1025.
[[58]]
Hendriksen M A H, Over E A B, Navis G, et al. Limited salt consumption reduces the incidence of chronic kidney disease: a modeling study. J Public Health (Oxf), 2018; 40(3): e351-e358.
[[59]]
Graudal N A, Hubeck-Graudal T, Jurgens G. Effects of low sodium diet versus high sodium diet on blood pressure, renin, aldosterone, catecholamines, cholesterol, and triglyceride. Cochrane Database Syst Rev, 2020; 12(12): CD004022.
[[60]]
Kidney Dis. Outcomes (KDIGO) CKD Work Group. 2013. KDIGO KDIGO 2012 clinical practice guideline for the evaluation and management of chronic. Kidney Int. Suppl, 2013; 3(1): 1-136.
[[61]]
Malhotra R, Lipworth L, Cavanaugh K L, et al. Protein intake and long-term change in glomerular filtration rate in the Jackson heart study. J Ren Nutr, 2 2018; 28(4): 245-250.
[[62]]
Esmeijer K, Geleijnse J M, et al. Dietary protein intake and kidney function decline after myocardial infarction: the alpha omega cohort. Nephrol Dial Transplant, 2020; 35(1): 106-115.
[[63]]
Haring B, Selvin E, Liang M, et al. Dietary protein sources and risk for incident chronic kidney disease: Results from the atherosclerosis risk in communities (ARIC) study. J Ren Nutr, 2017; 27(4): 233-242.
[[64]]
Lew Q L J, Jafar T H, Koh H W L, et al. Red meat intake and risk of ESRD. J Am Soc Nephrol, 2017; 28(1): 304-312.
[[65]]
Haring B, Selvin E, Liang M, et al. Dietary protein sources and risk for incident chronic kidney disease: results from the Atherosclerosis Risk in Communities (ARIC) Study. J Ren Nutr, 2017; 27(4): 233-242.
[[66]]
Wang Z, Bergeron N, Levison B S, et al. Impact of chronic dietary red meat, white meat, or non-meat protein on trimethylamine N-oxide metabolism and renal excretion in healthy men and women. Eur Heart J, 2019; 40(7): 583-594.
[[67]]
Lau W L, Savoj J, Nakata M B, et al . Altered microbiome in chronic kidney disease: systemic effects of gut-derived uremic toxins. Clin Sci (Lond), 2018; 132(5): 509-522.
[[68]]
Kalantar-Zadeh K, Fouque D. Nutritional management of chronic kidney disease. N Engl J Med, 2017; 377: 1765-1776.
[[69]]
Silva L, Moço S A, Antunes M L, et al. Dietary Acid Load and relationship with Albuminuria and Glomerular Filtration Rate in individuals with chronic kidney disease at Predialysis State. Nutrients, 2021; 14(1): 170.
[[70]]
Ho B B, Bergwitz C. FGF23 signalling and physiology. J Mol Endocrinol, 2021; 66(2): R23-R32.
[[71]]
Trujillo J, Ramírez V, Pérez J, et al. Renal protection by a soy diet in obese Zucker rats is associated with restoration of nitric oxide generation. Am J Physiol Renal Physiol, 2005;288(1): F108-F116.
[[72]]
Meneely G R, Ball C O. Experimental epidemiology of chronic sodium chloride toxicity and the protective effect of potassium chloride, Am. J. Med, 1958; 25(5): 713-725.
[[73]]
Di Iorio B R, Micco Di L, Marzocco S, et al. On behalf of ubi study group. Very Low-Protein Diet (VLPD) reduces metabolic acidosis in subjects with chronic kidney disease: the "Nutritional Light Signal" of the renal acid load. Nutrients, 2017; 9: 69.
[[74]]
Goraya N, Simoni J, Jo C H, et al. Treatment of metabolic acidosis in patients with stage 3 chronic kidney disease with fruits and vegetables or oral bicarbonate reduces urine angiotensinogen and preserves glomerular filtration rate. Kidney Int, 2014; 86: 1031-1038.
[[75]]
Jhee J H, Kee Y K, Park J T, et al. A diet rich in vegetables and fruit and incident CKD: A Community-Based Prospective cohort study. Am J Kidney Dis, 2019; 74(4): 491-500.
[[76]]
Rysz J, Franczyk B, Ciałkowska-Rysz A, et al. The effect of diet on the survival of patients with chronic kidney disease. Nutrients, 2017; 9(5): 495.
[[77]]
Phillips S M, Paddon-Jones D, Layman D K. Optimizing adult protein intake during catabolic health conditions. Adv Nutr, 2020; 11(4): S1058-S1069.
[[78]]
Sasai F, Roncal-Jimenez C, Rogers K, et al. Climate change and nephrology. Nephrol Dial Transplant, 2021; gfab258.
[[79]]
He L, Xue B, Wang B, et al. Impact of high, low, and non-optimum temperatures on chronic kidney disease in a changing climate, 1990- 2019: A global analysis. Environ Res, 2022;
[[80]]
Hong J, Xuelong Z. Effects of cold stimulus on the histology structure of skeletal muscle and senven visceral organs in rats. Chin J Vet Sci, 2019; 39(1): 105-112.
[[81]]
Lovallo W. The cold pressor test and autonomic function: a review and integration. Psychophysiology, 1975; 12(3): 268-82.
[[82]]
Sun L, Yan J, Goh H J, et al. Fibroblast growth factor-21, leptin, and adiponectin responses to acute cold-induced brown adipose tissue activation. J Clin Endocrinol Metab, 2020; 105(3): e520-e531.
[[83]]
Amiya E, Watanabe M, Komuro I. The relationship between vascular function and the autonomic nervous system. Ann Vasc Dis, 2014; 7: 109- 119.
[[84]]
Mao W, Jin X, Wang H, et al. The Association between resting heart rate and urinary albumin/creatinine ratio in middle-aged and elderly Chinese population: a cross-sectional study. J Diabetes Res, 2019; 2019: 9718370.
[[85]]
Chou Y H, Huang W L, Chang C H, et al. Heart rate variability as a predictor of rapid renal function deterioration in chronic kidney disease patients. Nephrology (Carlton), 2019; 24(8): 806-813.
[[86]]
Efremova A, Colleluori G, Thomsky M, et al. Biomarkers of browning in cold exposed siberian adults. Nutrients, 2020; 12(8): 2162.
[[87]]
Hanssen M J, Broeders E, Samms R J, et al. Serum FGF 21 levels are associated with brown adipose tissue activity in humans. Sci Rep, 2015; 5: 10275.
[[88]]
Villarroya F, Cereijo R, Villarroya J, et al. Brown adipose tissue as a secretory organ. Nat Rev Endocrinol, 2017; 13(1): 26-35.
[[89]]
Ameka M, Markan K R, Morgan D A, et al. Liver Derived FGF 21 maintains core body temperature during acute cold exposure. Sci Rep, 2019; 9(1): 630.
[[90]]
Sepa-Kishi D M, Ceddia R B. Circulating fibroblast growth factor 21 is reduced, whereas its production is increased in a fat depot-specific manner in cold-acclimated rats. Adipocyte, 2018; 7(4):238-247.
[[91]]
Zouhar P, Janovska P, Stanic S, et al. A pyrexic effect of FGF 21 independent of energy expenditure and UCP1. Mol Metab, 2021; 53: 101324.
[[92]]
Suassuna P G A, Paula R B, Sanders-Pinheiro H, et al. Fibroblast growth factor 21 in chronic kidney disease. J Nephrol, 2019; 32(3): 365-377.
[[93]]
Kondo Y, Komaba H, Fukagawa M. Endocrine fibroblast growth factors as potential biomarkers for chronic kidney disease. Expert Rev Mol Diagn, 2020; 20(7): 715-724.
[[94]]
Yusuf S, Piedimonte G, Auais A, et al. The relationship of meteorological conditions to the epidemic activity of respiratory syncytial virus. Epidemiol Infect, 2007; 135(7): 1077-1090.
[[95]]
Ciruela P, Broner S, Izquierdo C, et al. Invasive pneumococcal disease rates linked to meteorological factors and respiratory virus circulation (Catalonia, 2006-2012). BMC Public Health, 2016; 16: 400.
[[96]]
Nasr S H, Radhakrishnan J, D'Agati V D. Bacterial infection-related glomerulonephritis in adults. Kidney Int, 2013; 83(5): 792-803.
[[97]]
Joo S Y, Park M J, Kim K H, et al. Cold stress aggravates inflammatory responses in an LPS-induced mouse model of acute lung injury. Int J Biometeorol, 2016; 60(8): 1217-1225.
[[98]]
Lee J, Park E J, Hwang J W, et al. CIP2A expression is associated with synovial hyperplasia and invasive function of fibroblast-like synoviocytes in rheumatoid arthritis. Rheumatol Int, 2012; 32(7): 2023-2030.
[[99]]
Eimonte M, Eimantas N, Daniuseviciute L, et al. Recovering body temperature from acute cold stress is associated with delayed proinflammatory cytokine production in vivo. Cytokine, 2021; 143: 155510.
[[100]]
Hochachka P W. Defense strategies against hypoxia and hypothermia. Science, 1986; 231(4735): 234-221.
[[101]]
Honda H M, Korge P, Weiss J N. Mitochondria and ischemia/ reperfusion injury. Ann N Y Acad Sci, 2005; 1047: 248-258.
[[102]]
Dugbartey G J, Hardenberg M C, Kok W F, et al. Renal mitochondrial response to low temperature in non-hibernating and hibernating species. Antioxid Redox Signal, 2017; 27(9): 599-617.
[[103]]
Xie Z, Xia W, Zhang Z, et al. Prevalence of Vitamin D inadequacy among Chinese postmenopausal women: a nationwide, multicenter, cross-sectional study. Front Endocrinol (Lausanne), 2018; 9: 782.
[[104]]
Krummel T, Ingwiller M, Keller N, et al. Effects of high- vs low-dose native vitamin D on albuminuria and the renin-angiotensin-aldosterone system: a randomized pilot study. Int Urol Nephrol. 2022; 54(4): 895-905.
[[105]]
Yu Q, Qiao Y, Liu D, et al. Vitamin D protects podocytes from autoantibodies-induced injury in lupus nephritis by reducing aberrant autophagy. Arthritis Res. Ther, 2019; 21: 19.
[[106]]
An X, Wen X, Liu Y. Paricalcitol inhibits renal inflammation by promoting vitamin D receptor-mediated sequestration of NF-kappaB signaling. J Am Soc Nephrol, 2008; 19(9):1741-1752.
[[107]]
Gembillo G, Siligato R, Amatruda M, et al. Vitamin D and glomerulonephritis. Medicina (Kaunas), 2021; 57(2): 186.
[[108]]
Lutz J, Jurk R N K. Platelets in advanced chronic kidney disease: two sides of the coin. Semin Thromb Hemost, 2020; 46(3): 342-356.
[[109]]
Kelly J T, Su G, Zhang L, et al. Modifiable lifestyle factors for primary prevention of CKD: a systematic review and meta-analysis. J Am Soc Nephrol, 2021; 32(1): 239-253.
[[110]]
Lee S, Kang S, Joo Y S, et al. Smoking, smoking cessation, and progression of Chronic Kidney Disease: results from KNOW-CKD study. Nicotine Tob Res, 2021; 23(1): 92-98.
[[111]]
Joo Y S, Koh H, Nam K H, et al. Alcohol consumption and progression of chronic kidney disease: results from the Korean cohort study for outcome in patients with chronic kidney disease. Mayo Clin Proc, 2020; 95(2): 293-305.
[[112]]
Yuan H C, Yu Q T, Bai H, et al. Alcohol intake and the risk of chronic kidney disease: results from a systematic review and dose-response meta-analysis. Eur J Clin Nutr, 2021; 75(11): 1555-1567.
[[113]]
Zhang N H, Luo R, Cheng Y C, et al. Leisure-Time physical activity and mortality in CKD: a 1999-2012 NHANES analysis. Am J Nephrol, 2020; 51(11): 919-929.
[[114]]
Kuźma Ł, Małyszko J, Bachórzewska-Gajewska H, et al. Exposure to air pollution and renal function. Sci Rep, 2021; 11(1): 11419.
[[115]]
Chang T I, Lim H, Park C H, et al. Association between income disparities and risk of chronic kidney disease: a nationwide cohort study of seven million adults in Korea. Mayo Clin Proc, 2020; 95(2): 231-242.
[[116]]
Tripathy S, Cai X, Adhikari A, et al. Association of educational attainment with incidence of CKD in young adults. Kidney Int Rep, 2020; 5(12): 2256-2263.
PDF(478 KB)

Accesses

Citations

Detail

Sections
Recommended

/