A cellular automata model for simulating fed-batch penicillin fermentation process

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  • Electronic Information and Control Engineering College, Beijing University of Technology, Beijing 100022, China;

Published date: 05 Jun 2006

Abstract

A cellular automata model to simulate penicillin fed-batch fermentation process (CAPFM) was established in this study, based on a morphologically structured dynamic penicillin production model, that is in turn based on the growth mechanism of penicillin producing microorganisms and the characteristics of penicillin fed-batch fermentation. CAPFM uses the three-dimensional cellular automata as a growth space, and a Moore-type neighborhood as the cellular neighborhood. The transition rules of CAPFM are designed based on mechanical and structural kinetic models of penicillin batch-fed fermentation processes. Every cell of CAPFM represents a single or specific number of penicillin producing microorganisms, and has various state. The simulation experimental results show that CAPFM replicates the evolutionary behavior of penicillin batch-fed fermentation processes described by the structured penicillin production kinetic model accordingly.

Cite this article

Yu Naigong, Ruan Xiaogang . A cellular automata model for simulating fed-batch penicillin fermentation process[J]. Frontiers in Biology, 2006 , 1(2) : 195 -202 . DOI: 10.1007/s11515-006-0024-9

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