MicroRNAs and their role in viral infection

Expand
  • College of Life Science and Tianjin State Laboratory of Microbial Functional Genomics, Nankai University, Tianjin 300071, China

Published date: 05 Mar 2007

Abstract

Recently, a class of about 22 nucleotides (nt) small RNA has been discovered in many eukaryotes, termed microRNAs (miRNAs), which have a variety of functions. Many recent findings have demonstrated that viruses can also encode their own miRNAs. Meanwhile, other findings reveal a relationship between host miRNA and viral infection. These findings suggest a tight relationship between host and viral infection via miRNA pathway. This article introduces the miRNAs encoded by viruses and reviews the advances of the interaction of the mammalian host miRNAs and viral infection.

Cite this article

MU Junjie, YAO Xue, CHEN Qimin, GENG Yunqi, QIAO Wentao . MicroRNAs and their role in viral infection[J]. Frontiers in Biology, 2007 , 2(1) : 15 -20 . DOI: 10.1007/s11515-007-0002-x

Outlines

/