Innate immune exploitation by a model herpesvirus

Acknowledgements

Research of the Feng laboratory is supported by the Endowed Scholar Program of UT Southwestern, National Cancer Institute, and American Cancer Society.

References

1 Akira S, Uematsu S, Takeuchi O (2006). Pathogen recognition and innate immunity.Cell, 124(4): 783-801

PMID

2 Beignon A S, McKenna K, Skoberne M, Manches O, DaSilva I, Kavanagh D G, Larsson M, Gorelick R J, Lifson J D, Bhardwaj N (2005). Endocytosis of HIV-1 activates plasmacytoid dendritic cells via Toll-like receptor-viral RNA interactions.J Clin Invest, 115(11): 3265-3275

PMID

3 Boshoff C, Weiss R A (2001). Epidemiology and pathogenesis of Kaposi’s sarcoma-associated herpesvirus.Philos Trans R Soc Lond B Biol Sci, 356(1408): 517-534

PMID

4 Brown H J, Song M J, Deng H, Wu T T, Cheng G, Sun R (2003). NF-kappaB inhibits gammaherpesvirus lytic replication.J Virol, 77(15): 8532-8540

PMID

5 Carbone A, Cesarman E, Spina M, Gloghini A, Schulz T F (2009). HIV-associated lymphomas and gamma-herpesviruses.Blood, 113(6): 1213-1224

PMID

6 Cavert W, Notermans D W, Staskus K, Wietgrefe S W, Zupancic M, Gebhard K, Henry K, Zhang Z Q, Mills R, McDade H, Schuwirth C M, Goudsmit J, Danner S A, Haase A T (1997). Kinetics of response in lymphoid tissues to antiretroviral therapy of HIV-1 infection.Science, 276(5314): 960-964

PMID

7 Chen Z J, Parent L, Maniatis T (1996). Site-specific phosphorylation of IkappaBalpha by a novel ubiquitination-dependent protein kinase activity.Cell, 84(6): 853-862

PMID

8 Dong X, Feng H, Sun Q, Li H, Wu T T, Sun R, Tibbetts S A, Chen Z J, Feng P, Früh K (2010). Murine gamma-herpesvirus 68 hijacks MAVS and IKKbeta to initiate lytic replication.PLoS Pathog, 6(7): e1001001

PMID

9 Fitzgerald K A, McWhirter S M, Faia K L, Rowe D C, Latz E, Golenbock D T, Coyle A J, Liao S M, Maniatis T (2003). IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway.Nat Immunol, 4(5): 491-496

PMID

10 Gargano L M, Forrest J C, Speck S H (2009). Signaling through Toll-like receptors induces murine gammaherpesvirus 68 reactivation in vivo.J Virol, 83(3): 1474-1482

PMID

11 Gargano L M, Moser J M, Speck S H (2008). Role for MyD88 signaling in murine gammaherpesvirus 68 latency.J Virol, 82(8): 3853-3863

PMID

12 Gregory S M, West J A, Dillon P J, Hilscher C, Dittmer D P, Damania B (2009). Toll-like receptor signaling controls reactivation of KSHV from latency.Proc Natl Acad Sci USA, 106(28): 11725-11730

PMID

13 Gringhuis S I, van der Vlist M, van den Berg L M, den Dunnen J, Litjens M, Geijtenbeek T B (2010). HIV-1 exploits innate signaling by TLR8 and DC-SIGN for productive infection of dendritic cells.Nat Immunol, 11(5): 419-426

PMID

14 Heil F, Hemmi H, Hochrein H, Ampenberger F, Kirschning C, Akira S, Lipford G, Wagner H, Bauer S (2004). Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8.Science, 303(5663): 1526-1529

PMID

15 Medzhitov R (2007). Recognition of microorganisms and activation of the immune response.Nature, 449(7164): 819-826

PMID

16 Meier A, Alter G, Frahm N, Sidhu H, Li B, Bagchi A, Teigen N, Streeck H, Stellbrink H J, Hellman J, van Lunzen J, Altfeld M (2007). MyD88-dependent immune activation mediated by human immunodeficiency virus type 1-encoded Toll-like receptor ligands.J Virol, 81(15): 8180-8191

PMID

17 Mercurio F, Zhu H, Murray B W, Shevchenko A, Bennett B L, Li J, Young D B, Barbosa M, Mann M, Manning A, Rao A (1997). IKK-1 and IKK-2: cytokine-activated IkappaB kinases essential for NF-kappaB activation.Science, 278(5339): 860-866

PMID

18 Orenstein J M, Fox C, Wahl S M (1997). Macrophages as a source of HIV during opportunistic infections.Science, 276(5320): 1857-1861

PMID

19 Pierce J W, Schoenleber R, Jesmok G, Best J, Moore S A, Collins T, Gerritsen M E (1997). Novel inhibitors of cytokine-induced IkappaBalpha phosphorylation and endothelial cell adhesion molecule expression show anti-inflammatory effects in vivo.J Biol Chem, 272(34): 21096-21103

PMID

20 Sharma S, tenOever B R, Grandvaux N, Zhou G P, Lin R, Hiscott J (2003). Triggering the interferon antiviral response through an IKK-related pathway.Science, 300(5622): 1148-1151

PMID

21 Sun L, Liu S, Chen ZJ (2010). SnapShot: pathways of antiviral innate immunity. Cell, 140(3): 436-436.e2.

22 Virgin H W 4th, Latreille P, Wamsley P, Hallsworth K, Weck K E, Dal Canto A J, Speck S H (1997). Complete sequence and genomic analysis of murine gammaherpesvirus 68.J Virol, 71(8): 5894-5904

PMID

23 Zhang B, Wang Y Y, Shu H B (2010). Regulation of virus-triggered type I interferon signaling by cellular and viral proteins.Front Biol, 5(1): 12-31