Electrospun composite nanofibrous membrane as wound dressing with good adhesion

Rui NIU, Jing QIAO, Hang YU, Jun NIE, Dongzhi YANG

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PDF(408 KB)
Front. Chem. China ›› 2011, Vol. 6 ›› Issue (3) : 221-226. DOI: 10.1007/s11458-011-0244-7
RESEARCH ARTICLE

Electrospun composite nanofibrous membrane as wound dressing with good adhesion

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Abstract

A photopolymerizationable mimic mussel protein structure monomer, dopamine methacrylamide (DMA), was synthesized. The photopolymerization of DMA was analysed by series real time near infrared spectroscopy (SRTIR). Dopamine methacrylamide/poly(ethylene oxide) (DMA/PEO) nanofibers were successfully prepared by electrospinning of aqueous DMA/PEO solution. Biocompatible nanofibrous membrane with good adhesion was produced by photocuring from the DMA/PEO nanofibers. The surface characterization and structure of the composite nanofibrous membrane were characterized by a scanning electron microscopy (SEM) and contact angle measurements. For identifying the potential crystalline of curing, a XRD method was used through comparing diffraction data. In the cell adhesion test we utilized the mouse fibroblast (L929) to exam the various use of the nanofibrous membrane as scaffolding materials for skin regeneration.

Keywords

electrospinning / wound dressing / adhesives

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Rui NIU, Jing QIAO, Hang YU, Jun NIE, Dongzhi YANG. Electrospun composite nanofibrous membrane as wound dressing with good adhesion. Front Chem Chin, 2011, 6(3): 221‒226 https://doi.org/10.1007/s11458-011-0244-7

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Acknowledgements

The authors would like to thank the National Natural Science Foundation of China (Grant No. 50803004), Beijing Natural Science Foundation (Grant No. 2112033, Study on the molecular design and properties of new photocurable antifouling coatings) and the Fundamental Research Funds for the Central Universities (No. ZZ1115) for the financial support.

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2014 Higher Education Press and Springer-Verlag Berlin Heidelberg
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