Synthesis of -tricalcium phosphate using sol-gel self-propagating combustion method

Abstract

?-tricalcium phosphate (?-TCP) is a key component of natural bone like hydroxyapatite. Pure and uniformly nanosized ?-tricalcium phosphate powders were synthesized using a sol-gel self-propagating combustion method by using citric acid as a reductant and using fuel and nitrate as the oxidant. The thermal decomposition of nitrate-citrate xero-gel was studied by thermogravimetric-differential thermal analysis (TG/DTA) and the process mechanism of self-propagating combustion were discussed. The resulting powders calcined at 1023, 1173 and 1273 K were characterized by Ca/P ratio analysis, X-ray diffraction (XRD), scanning electron microscopy (SEM) and transmission electron microscopy (TEM). It was found that the as-prepared powders were pure ?-tricalcium phosphate having regular porous surface very similar to coral.

References

1. Ben-Nissan B, Milev A, Vago R . Morphology of sol-gel derived nano-coated coralline hydroxyapatite. Biomaterials, 2004, 25: 4971–5. doi:10.1016/j.biomaterials.2004.02.006
2. Gan L, Wang J . Alex Tache. Calcium phosphatesol-gel-derived thin films on porous-surfaced implants for enhancedosteoconductivity. Part II: Short-term in vivo studies. Biomaterials, 2004, 25(22): 5313–21. doi:10.1016/j.biomaterials.2003.12.039
3. Burg K J L, Kellam J F . Biomaterial developmentsfor bone tissue engineering. Biomaterials, 2000, 21: 2347–59. doi:10.1016/S0142-9612(00)00102-2
4. Wim den Hollander, Petr Patka, Christel P A T Klein, Guido A K . Heidendal.Macroporous calcium phosphate ceramics for bone substitution:a tracer study on biodegradation with ⁴⁵Ca tracer. Biomaterials, 1991, 12(6): 569–573. doi:10.1016/0142-9612(91)90053-D
5. Sasikumar S, Vijayaraghavan R . Solution Combustion Synthesisof Bioceramic Calcium Phosphates by single and mixed fuels–Acomparative study, Ceramics International (2007). doi: 10.1016/j. ceramint, 2007, 03: 009
6. Shu C, Xianzhu Y, Zhangyin X, Guohua X, Hong L . Synthesis and sintering of nanocrystallinehydroxyapatite powders by gelatin-based precipitation method. Ceram Int, 2007, 33: 193–6. doi:10.1016/j.ceramint.2005.09.001
7. Silva V V, Lameiras F S, Domingues R Z . Synthesis and characterization of calcia partially stabilizedzirconia-hydroxyapatite powders prepared by co-precipitation method. Ceram Int, 2001, 27: 615–20. doi:10.1016/S0272-8842(00)00122-X
8. Cuneyt Tas A . Combustionsynthesis of calcium phosphate bioceramic powders. J E uro Ceram Soc, 2000, (2): 389–394
9. Kingsley J J, Patil K C . A novel combustion processfor the synthesis of fine particle-alumina and related oxide materials. Mater Lett, 1988, 6: 427–32. doi:10.1016/0167-577X(88)90045-6
10. Liu D M, Yang Q, Troczynski T, Tseng W J . Aging effecton the phase evolution of water-based sol-gel hydroxyapatite. Biomaterials, 2002, 23: 1227–36. doi:10.1016/S0142-9612(01)00242-3
11. Han Y C, Li S P . Synthesis and sintering ofnanocrystalline hydroxyapatite powders by citric acid sol-gel combustionmethod. Mater Res Bull, 2004, 39(1): 25–32. doi:10.1016/j.materresbull.2003.09.022
12. Qi X W, Zhou Ji, Yue Z X, Gui Z L, Li L T . Auto-combustion synthesis of nanocrystallineLaFeO₃. Mater ChemPhys, 2002, 78(1): 25–9. doi:10.1016/S0254-0584(02)00341-3
13. Ding Z S, Weng W J, Yang J . Application of chemical complex method in the processof sol-gel. J Chin Ceram Soc, (Chinese) . 1995, 23(5): 571–579
14. Yin B Y, Wang L S, Fan Y . Application research of glycol in complex sol-gel method. J Chin Ceram Soc, 1999, 27(3): 337–341 (in Chinese)
15. Zhang J, Wang Z F . Precise Measurement of Caand P Content in Hydroxyapatite by Chemical Analysis. Bull Chin Ceram Soc, 2007, 26(1): 186–189 (in Chinese)