2026-04-21 2026, Volume 6 Issue 2

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  • Review
    Suibi Yang, Hongjie Shen, Jie Yang, Yuxing Wang, Jing Zhang, Lifeng Xing, Pengmin Zhou, Pengpeng Chen, Hongying Ni, Yuetian Yu, Zhongheng Zhang

    Acute kidney injury (AKI) is a common and serious complication after cardiac surgery, affecting 10%-40% of patients. It worsens patient outcomes and consumes significant healthcare resources. Its pathophysiology is complex and involves ischemia-reperfusion injury, inflammatory responses, and endothelial dysfunction. Artificial intelligence (AI) offers considerable potential to improve the management of this condition. AI models can integrate multimodal data, including preoperative clinical profiles, intraoperative hemodynamics, and postoperative laboratory values, thereby enabling early prediction of AKI. By identifying distinct clinical subtypes, AI may support personalized therapeutic strategies. Furthermore, it may improve prognostic assessments, allowing more precise risk stratification for both cardiac and renal outcomes. However, current applications face challenges, including inconsistent data quality, limited model interpretability, and high implementation costs. Existing models are also constrained by the range of variables they incorporate. Future technological advances may enable the analysis of a broader array of variables, potentially revealing novel biomarkers and clinically useful combinations of indicators. Such progress could advance precision medicine in this field, ultimately improving patient care and optimizing clinical workflows.

  • Review
    Eunice Yang, Harrison J. Howell, Elan Schonfeld, Joshua Fuller, Farhan Khan, Bhargav Ayloo, Chiemela Izima, Shailen G. Sampath, Anthony J. Tang, Nathaniel W. Rolfe, Terrence Green, Dean Chou, Andrew K. Chan

    Artificial intelligence is rapidly reshaping healthcare, with computer vision enabling automated interpretation of imaging across a wide range of clinical applications. Given its heavy reliance on imaging across perioperative settings, spine surgery is particularly well-suited for the integration of computer vision technologies. At the same time, spine surgery is among the fastest-growing and most resource-intensive specialties, with rising demands that underscore the need for technologies capable of enhancing precision, efficiency, and safety. In this narrative review, we will synthesize current applications of computer vision across the spine surgery workflow, outline key barriers for implementation, and discuss future directions for translating these tools into widespread clinical practice. Computer vision tools span a spectrum of maturity, with some already achieving clinical deployment for spinopelvic parameter measurement, pathology detection, and surgical planning, while intraoperative applications represent the most actively developing frontier. These innovations may redefine the standard of care in spine surgery, enabling a new era of surgical performance and data-informed decision-making.

  • Original Article
    Francesca Tozzi, Seyed Amir Mousavi, Robbe De Muynck, Dario Quintini, Adris Molnar, Femke Van Vaerenbergh, Xander De Lille, Matthias Van Liefferinge, Wim Ceelen, Wouter Willaert, Wesley De Neve, Niki Rashidian

    Aim: To evaluate deep learning models for anatomical structure and peritoneal metastasis (PM) detection and segmentation during staging laparoscopy (SL) using a phase-independent dataset, and to quantify how annotation strategy and spatial representation relate to predictive performance.

    Methods: A checklist covering 25 anatomical structures, one surgical instrument, and PM was defined. Detection models (YOLOv9, Co-DETR) and segmentation models (SegFormer, Mask2Former) were trained under two label configurations. Videos were split at the video level (60/20/20). To quantify annotation distribution and spatial representation, two class-level descriptors were derived from the training set: object count and area fraction (percentage of image area occupied by each class). Class-level associations between these descriptors and test-set performance [F1-score, Intersection over Union (IoU)] were evaluated using Spearman correlation.

    Results: Thirty SL videos yielded 2,309 annotated frames (1,304/433/572 for training/validation/testing). YOLOv9 reached mean mAP@50 of 0.52 and 0.61; Mask2Former achieved mean IoU of 0.51 and 0.61 and F1-scores of 0.65 and 0.73 for Sets A and B, respectively. Despite 4,094 annotations, PM remained difficult to segment (IoU 0.29-0.30; F1-score 0.45-0.46), due to low area fraction and high heterogeneity. For IoU, area fraction showed stronger correlations with performance than object count (ρ up to 0.66 vs. 0.48). Similar differences were observed for F1-score.

    Conclusions: Anatomical detection and segmentation during SL are feasible but limited by small-target representation and heterogeneous intra-abdominal context. Spatial representation is more closely associated with segmentation performance than annotation frequency, supporting annotation strategies that address sparse pixel coverage in phase-independent intra-abdominal models.