Chemical constituents and biological activities of Scutellaria barbata

Abstract

Scutellaria barbata D.Don (S. barbata), is a perennial herb of Labiatae scutellaria, with a variety of chemical constituents and biological activities. Its chemical constituents include terpenoids, flavonoids, polysaccharides, volatile compounds and trace elements. Among the terpenoids, diterpenoids are abundant, particularly neocrotane diterpenoids. More than 70 flavonoids have been identified as important pharmacological components and quality control markers. Polysaccharides play an important role in its anti-tumor efficacy. Volatile compounds have antibacterial effects, and trace elements are associated with active ingredients. In terms of pharmacological activity, S. barbata exhibits anti-tumor, hepatoprotective, anti-inflammatory, immunomodulatory, antioxidant and antibacterial effects. This review aims to summarize the research progress of S. barbata and provide a theoretical basis for its clinical application.

Keywords

Scutellaria barbata / chemical constituent / biological activity

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