The management of minor ischemic stroke presents significant challenges due to variability in the applicationof neuroimaging protocols and endovascular treatment (EVT). The lack of consensus on the need for computed tomographyangiography (CTA) in these cases highlights the importance of investigating the prevalence and clinical implications oflarge vessel occlusion (LVO) in this population.

Analysis of the multicenter CODICT registry in patientswith minor ischemic stroke (National Institutes of Health Stroke Scale (NIHSS) score ≤5) treated at tertiary stroke alert(SA) centers in the Valencian Community between July 1, 2020 and November 30, 2023. The frequency of LVO, definedas occlusions in the internal carotid artery, vertebral artery, basilar artery, and critical segments of the middle (M1, M2),anterior (A1, A2), and posterior (P1, P2) cerebral arteries, was evaluated using CTA

A total of 5473 SA activationswere identified during the study period. A total of 833 patients suffered a minor ischemic stroke. LVO was observed in17.5% (n = 146) of minor strokes on CTA. EVT was performed in 48.6% (n = 71) of patients with minor stroke and LVO.The most frequently occluded vessels were the middle cerebral artery (MCA) in its M1 and M2 segments, both in 35.6%(n = 52) of cases. However, the vessels most frequently treated with EVT were in the M1, in 29.5% (n = 43) of cases,followed by the M2, in 10.9% (n = 16) of cases.

This study highlights the importance of performing CTAin all patients who meet SA activation criteria, regardless of clinical severity. The presence of LVO changed the clinicalmanagement in almost half of the patients with minor stroke and LVO.

Virtual reality (VR) generates a virtual environment with which one can interact as if it were real. In Stroke,which represents one of the highest causes of cognitive impairment in Europe, the use of VR in cognitive rehabilitation hasbeen studied through the performance of different types of tasks, which could have different impacts. For this reason, theobjective of this study was to review the use of VR tasks based exclusively on daily activities for the cognitive rehabilitationof people with stroke over 18 years of age.

A search was carried out of the databases PubMed, Web of Science,and Scopus, obtaining 531 articles that, after applying inclusion/exclusion criteria, were reduced to eight (six randomizedclinical trials and two quasi-experimental studies).

The number of positive results was higher than the number ofnegative results only in global cognitive function. In specific cognitive functions the number of positive results was lowerthan the negatives.

These results highlight the need to carry out more studies with larger samples to obtainrobust results and conclusions. Furthermore, this study highlights the value of research in this topic due to the interestinglines of future research.