In the modern world, gestational diabetes mellitus (HDM) is a common disorder of carbohydrate metabolism in pregnant women, that indicates to the undoubted relevance of this problem in women of the reproductive age. High values of glucose concentration adversely affect not only the pregnant’s body, but also the fetus, that confirms the importance of timely diagnosis of GDM. In the article there was executed analysis both of modern literature data, testifying the role of this pathology in the occurrence of complications during pregnancy, and modern methods of diagnostics and treatment.

Laparoscopic ovarian drilling is now considered to be a safe and effective surgical method. The frequency of the onset of pregnancy is similar tothat of the therapeutic methods of ovulation induction. At the same time, a lower risk of ovarian hyperstimulation syndrome and multiple pregnancies makes drilling more preferable to gonadotropin therapy. Despite the advantages of this method of surgical treatment, the issue of possible complications still remains to be relevant.

At present, the problem of hormonal contraception in women with autoimmune thyroiditis is quite relevant and poorly understood. There is a few works devoted to the study of the effectiveness and acceptability of hormonal contraceptives in this group of women. This review considers characteristics of the reproductive health of autoimmune thyroiditis female patients and assesses the effect of hormonal contraceptives on the course of the underlying disease and the indices of the immune system in autoimmune thyroiditis female patients of the reproductive age.

Hypothyreosis is one of the most common endocrine pathologies closely related with the reproductive system. In female patients with hypofunction of the thyroid gland, various disorders occur in the reproductive system: menstrual cycle deteriorations, miscarriage, infertility. Therefore, the study of thyroid function should be carried out as a screening in women planning pregnancy, as well as in infertile couples in the treatment of the infertility. When hypothyreosis is detected, L-thyroxine replacement therapy is necessary.

Women’s obesity and reproductive health are linked at the hormonal level. Against the background of the obesity, various disorders of the menstrual function occur, the cycle of ovulation is changing, that eventually leads to the endocrine infertility. The normalization of the body weight is the way both the o restoration of reproductive functions of the female body, as well as the solution of the problem of endocrine infertility.

Fertility in women with congenital dysfunction of the adrenal cortex (CDAC) due to the insufficiency of 21-hydroxylase (n21-OH) is presumed to decrease, especially in women with classic salt-losing type. Several factors contribute to the development of subfertility: an excess of androgens, adrenal hypersecretion of progesterone, the consequences of the reconstructive genital surgery, a syndrome of secondary polycystic ovaries and psychosexual factors. Adequate glucocorticoid therapy and the improvement of surgical and psychological care can contribute to the optimization of infertility in CDAC patients, even in classical variant women. This review contains up-to-date information on reproductive outcomes in CDAC women due to n21-OH, infertility and pregnancy problems.