Transplanted fetal cells are involved in the pathological process in Parkinson's disease

References

[1] Jankovic J. Parkinson’s disease: clinical features and diagnosis. J. Neurol. Neurosurg. Psychiatr. 2008; 79(4): 368—76.

[2] Lepoutre A., Devos D., Blanchard-Dauphin A. A specific clinical pattern of camptocormia in Parkinson’s disease. J. Neurol. Neurosurg. Psychiatr. 2006; 77(11): 1229-34.

[3] Jenner P. Oxidative mechanisms in nigral cell death in Parkinson’s disease. Mov. Disord. 1998; 13(1): 24—34.

[4] Cotzias G. Manganese, melanins and the extrapyramidal system. J. Neurosurg. 1966; 24 (1): 170-80.

[5] Lang A.E., Obeso J.A. Challenges in Parkinson’s disease: restoration of the nigrostriatal dopamine system is not enough. Lancet Neurol. 2004; 3(5): 309-16.

[6] Wernig M., Zhao J., Pruszak J. Neurons derived from reprogrammed fibroblasts functionally integrate into the fetal brain and improve symptoms of rats with Parkinson’s disease. PNAS 2008; 105(15): 5856—61.

[7] Freed C.R., Greene P.E., Breeze R.E. et al. Transplantation of embryonic dopamine neurons for severe Parkinson’s disease. N. Engl. J. Med. 2001; 344: 710-19.

[8] Bjцrklund A., Dunnett S.B., Brundin P. et al. Neural transplantation for the treatment of Parkinson’s disease. Lancet Neurol. 2003; 2(7): 437-15.

[9] Olanow C.W., Perl D.P., DeMartino G.N. et al. Lewy-body formation is an aggresome-related process: a hypothesis. Lancet Neurol. 2004; 3(8): 496-503.

[10] Duffy P., Tennyson V. Phase and electron microscopic observations of Lewy bodies and melanin granules in the substantia nigra and locus coeruleus in Parkinson’s disease. J. Neuropathol. Exp. Neurol. 1965; 24: 398-414

[11] Li J.-Y., Englund E., Holton J.L. et al. Lewy bodies in grafted neurons in subjects with Parkinson’s disease suggest host-to-graft disease propagation. Nat. Med. 2008; 14(5): 501—3.

[12] Kordower J.H., Chu Y., Hauser R.A. et al. Lewy body—like pathology in long-term embryonic nigral transplants in Parkinson’s disease. Nat. Med. 2008; 14(5): 504-6.

[13] Mendez I., Vicuela A., Astradsson A. et al. Dopamine neurons implanted into people with Parkinson’s disease survive without pathology for 14 years. Nat. Med. 2008; 14(5): 507-9.

RIGHTS & PERMISSIONS

Eco-Vector