MicroRNAs modulate the activity of embryonic stem cell pluripotency factors Nanog, Oct4 and Sox2

References

[1] Bartel D.P. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 2004; 116: 281-97.

[2] Elbashir S.M., Lendeckel W., Tuschl T. RNA interference is mediated by 21- and 22-nucleotide RNAs. Genes Dev. 2001; 15: 188—200.

[3] Hammond S.M. Dicing and slicing: the core machinery of the RNA interference pathway. FEBS Lett. 2005; 579: 5822—9.

[4] Niwa H., Miyazaki J., Smith A.G. Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells. Nature Genet. 2000; 24: 372-6.

[5] Okumura-Nakanishi S., Saito M., Niwa H., Ishikawa F. Oct-3/4 and Sox2 regulate Oct-3/4 gene in embryonic stem cells. J. Biol. Chem. 2005; 280: 5307-17.

[6] Pan G., Thomson J.A. Nanog and transcriptional networks in embryonic stem cell pluripotency. Cell Res. 2007; 17: 42—9.

[7] Miranda K.C., Huynh T., Tay Y. et al. A pattern-based method for the identification of microRNA binding sites and their corresponding heteroduplexes. Cell 2006; 126: 1203—17.

[8] Slack F.J., Basson M., Liu Z. et al. The lin-41 RBCC gene acts in the C. elegans heterochronic pathway between the let-7 regulatory RNA and the LIN-29 transcription factor. Mol. Cell 2000; 5: 659—69.

[9] Lee R.C., Feinbaum R.L., Ambros V. The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell 1993; 75: 843-54.

[10] Bentwich I. Prediction and validation of microRNAs and their targets. FEBS Lett. 2005; 579: 5904-10.

[11] Rajewsky N. MicroRNA target predictions in animals. Nature Genet. 2006; 38: S8-13.

[12] Tay Y.M., Tam W.L., Ang Y.S. et al. MicroRNA-134 modulates the differentiation of mouse embryonic stem cells, where it causes post- transcriptional attenuation of Nanog and LRH1. Stem Cells 2008; 26: 17—29.

[13] http://www.pubmed.com (http://www.pubmed.com/)

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