Endothelial progenitor cells of the bone marrow are not involved in the processes of tumor angiogenesis and are not necessary for the growth of malignant neoplasms.

References

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[4] Lyden D., Нattori К., Dias S. et al. Impaired recruitment of one-marrow-derived endothelial and hematopoietic precursor cells locks tumor angiogenesis and growth. Nat. Мed. 2001; 7: 1194-201.

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[6] Нattori К., Dias S., Нeissig B. et al. Vascular endothelial growth factor and angiopoietin-1 stimulate postnatal hematopoiesis y recruitment of vasculogenic and hematopoietic stem cells. J. Exp. Мed. 2001; 193: 1005-14.

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