Expression of factor Oct4 is not required for self-renewal of somatic stem cells

References

[1] Boyer L.A., Lee T.I., Cole M.F. et al. Core transcriptional regulatory circuitry in human embryonic stem cells. Cell 2005; 122: 947-56.

[2] Feldman N„ Gerson A., Fang J. et al. G9a-mediated irreversible epigenetic inactivation of Oct-3/4 during early embryogenesis. Nat. Cell Biol. 2006; 8: 188-94.

[3] Moriscot C., De Fraipont F., Richard M.J. et al. Human bone marrow mesenchymal stem cellscan express insulin and key transcription factors of the endocrine pancreas developmental pathway upon genetic and/or microenvironmental manipulation in vitro. Stem Cells 2005; 23: 594-603.

[4] Morris R.J., Liu Y., Maries L. et al. Capturing and profiling adult hair follicle stem cells. Nat. Biotechnol. 2004; 22:411-7.

[5] Pallante B.A., Duignan I., Okin D. et al. Bone marrow Oct3/4+ cells differentiate into cardiac myocytes via age-dependent paracrine mechanisms. Circ. Res. 2007; 100: e1-e11.

[6] Ngan K.W., Jung S.M., Lee L.Y. et al. Immunohistochemical expression of 0CT4 in primary central nervous system germ cell tumours. J. Clin. Neurosci. 2008; 15:149-52.

[7] Webster J.D., Yuzbasiyan-Gurkan V., Trosko J.E., Chang C.C., Kiupel M. Expression of the embryonic transcription factor 0ct4 in canine neoplasms: a potential marker for stem cell subpopulations in neoplasia. Vet. Pathol. 2007; 44(6):893-900.

[8] Yamaguchi S., Yamazaki Y„ Ishikawa Y. et al. EWSR1 is fused to P0U5F1 in a bone tumor with translocation t[6;22][p21;q12]. Genes Chromosomes Cancer2005;43:217-22.

RIGHTS & PERMISSIONS

Eco-Vector