Natriuretic peptide and NT-proBNP is widely used to predict perioperative cardiac complications. In 62 elderly patients with concomitant cardiovascular disease were performent open prostatectomy surgery. In 32 patients had general anesthesia, 30 - spinal anesthesia. In the early postoperative period in the group with spinal anesthesia, recorded an increase in NT-proBNP more than 2 times. Regression of spinal block creates conditions for volume overload in patients with concomitant cardiovascular disease. Laboratory monitoring of NT-proBNP in the perioperative period in patients with concomitant cardiovascular disease can help indentify patients with preclinical form of heart failure and conduct timely corrective therapy.

The goal of the study was to test and assess difference in effect of different types of infused solution (Ringer's solution and HEX 130/0,4) on incidence of intraoperative nausea and vomiting (IONV) in patients undergone cesarean section under spinal anesthesia. Patients (n=76) were randomized into 2 groups depending on qualitative composition of infusion. There were no statistically significant difference between two studied group in demographic and obstetric parameters. No statistically significant difference of IONV incidence was found out between two groups. However small sample volumes doesn't allow asserting that Ringer's solution and HEX130/0,4 have equal effect on IONV incidence. Further studies with greater samples are needed to clarify this question.

The effect of anesthesia technique on neurological and hormonal status of newborns during surgical delivery was assessed in this study. All parturients undergone cesarean section were stratified into two comparable groups depending on the method of anesthesia. Spinal anesthesia was performed for patients in the first group (n=62) and total intravenous anesthesia was provided for patients in the second group (n=60). Glucose concentrations and cortisol levels in umbilical cord serum of newborns were studied. We found out that spinal anesthesia has no adverse effects on neurological status of newborns. The study results suggest that labour process that newborns experience under spinal anesthesia has beneficial effect on early adaptation course.

The article presents technique of instant femoral nerve block followed by catheter tunneling for prolonged femoral nerve block as a part of balanced anesthesia and multicomponent analgesia in knee surgery. The study included 23 patients (15 patients underwent knee replacement, 8 patients underwent knee ligamentoplasty). No cases of catheter migration, its entry site infection, as well as local anesthesia-related complications or toxic reactions were detected. The proposed technique decreases the risk of catheter migration and ensures the long-lasting and effective peripheral neuraxial block perioperatively.

We compared local infiltration analgesia and continuous femoral block with regard to analgesia and morphine demand during the first 24 h after TKA. The average pain at rest was marginally lower with LIA (1.6) than with femoral block (2.2). Total morphine consumption per kg was similar between the 2 groups. Both LIA and femoral block provide good analgesia after TKA. LIA may be considered to be superior to femoral block since it is cheaper and easier to perform.

In 2010, the American Society of Regional Anesthesia and Pain Medicine (ASRA) issued a practice advisory on local anesthetic systemic toxicity (LAST). The executive summary of this work contained a document that was intended to serve as checklist for the management of LAST. Based n testing the checklist during a simulated episode of LAST, ASRA has issued an updated version that should replace the previous 2010 version. Electronic copies of ASRA Checklist, suitable for laminatiojn and inclusion in a local anesthetic toxicity kit, are available from the ASRA Web site (www.asra.com).