Clinical features of pituitary adenomas in persons of young age

Abstract

We studied the results of the clinical examination and surgical treatment of 41 patients (25 (60,9%) women and 16 (39,1%) of men aged 18 to 30 years) with newly detected adenomas of the pituitary gland. It was found that for young patients characteristic is the long history of the disease. More likely to be diagnosed hormonally active (prolactinsecreting) pituitary adenoma. Tumors of the large and giant size women have higher secretion of prolactin compared to men with the same size of adenomas. The most frequently mentioned, a mixture of tumor growth. This variant was observed in most patients with hypersecretion of prolactin. Less marked unilateral laterocellar variant of tumor spread. The onset of the disease has manifested with optic-chiasm syndrome. Syndrome endocrine disorders presented increased levels of tropic hormones and disorders in the reproductive field, variability of lesions of the nervous system. We suggest that patients with tumors of the optic-chiasmal area should be observed and receive treatment in specialized medical centers together with neurosurgeons, neurologists, neuroophthalmologists. The provision of qualified medical care for patients with pituitary adenomas at the hospital stage and in the late postoperative period allows to ensure a high quality of life.

Keywords

pituitary adenoma / young age / endocrine disorders / Karnovsky’s scale / a benign tumor / optic-chiasm syndrome / hormonal / central nervous system

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