CHARACTERISTICS OF ADAPTATIONAL REACTIONS AND MALIGNANT SPREAD IN TUMORS OF VARIOUS LOCATIONS
G V Zhukova , A I Shikhlyarova , U M Gaziev , M S Zinkovich , A V Snezhko , Yu N Lazutin , A N Shevchenko , M I Bragina , A I Zhadobina
Medical academic journal ›› 2019, Vol. 19 ›› Issue (1S) : 47 -48.
CHARACTERISTICS OF ADAPTATIONAL REACTIONS AND MALIGNANT SPREAD IN TUMORS OF VARIOUS LOCATIONS
The character, intensity and quantitative indicator (QI) of general nonspecific adaptational reactions (AR) of the body were studied in patients with lung cancer (LC) or biliopancreatoduodenal cancer (BPDC) with various malignant spread. Poor AR characteristics were associated with the presence of metastases, but did not depend on the surgery volume. AR QI significantly differed depending on the metastatic status in patients with resectable LC receiving similar surgery treatment. AR QI in BPDC patients a day after radical pancreatoduodenal resection was higher than after bypass anastomosis. Thus, the studied AR characteristics demonstrated the state of systemic neuroimmune mechanisms of the nonspecific antitumor resistance of the body.
malignant spread / adaptational reactions / metastasis / surgery
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Zhukova G.V., Shikhlyarova A.I., Gaziev U.M., Zinkovich M.S., Snezhko A.V., Lazutin Y.N., Shevchenko A.N., Bragina M.I., Zhadobina A.I.
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