SEROTONIN LEVEL IN PERIPHERAL BLOOD AND THE BRAIN’S BIOELECTRICAL ACTIVITY IN YOUNG PEOPLE 15-17 YEARS

E V Krivonogova; L V Poskotinova; D B Demin; O A Stavinskaya

Medical academic journal ›› 2019, Vol. 19 ›› Issue (1S) :137 -138.

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SEROTONIN LEVEL IN PERIPHERAL BLOOD AND THE BRAIN’S BIOELECTRICAL ACTIVITY IN YOUNG PEOPLE 15-17 YEARS

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Abstract

The purpose of the work is to evaluate the features of the organization of the bioelectrical activity of the brain with different levels of serotonin in the serum of peripheral blood in young people 15-17 years old. The study involved 93 healthy girls and boys (15-17 years) of the Arkhangelsk region and the Nenets autonomous okrug. A serotonin level is determined in serum by enzyme immunoassay using a set of “Serotonin ELISA”. The electroencephalogram (EEG) power spectrum (PS) in the alpha, beta and theta frequencies ranges was recorded using an electroencephalograph “Encephalan” (Medicom, Taganrog). Age-dependent electroencephalogram (EEG) patterns is associated with the level of serotonin in peripheral blood in adolescents. On the background of a higher level of serotonin in the blood, compared to girls, boys have localized associations of theta and beta1 activity of EEG and serotonin levels, mainly in the right frontal-temporal region. In girls, the spectral power level of the EEG theta activity is more dependent on the level of serotonin in the blood, and a greater number of brain areas are involved in correlation interactions in comparison with young men (temporal regions on the left and frontal, central, parietal regions of both hemispheres of the brain).

Keywords

serotonin / EEG / adolescents

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E V Krivonogova, L V Poskotinova, D B Demin, O A Stavinskaya. SEROTONIN LEVEL IN PERIPHERAL BLOOD AND THE BRAIN’S BIOELECTRICAL ACTIVITY IN YOUNG PEOPLE 15-17 YEARS. Medical academic journal, 2019, 19(1S): 137-138 DOI:

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References

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