STRUCTURAL AND FUNCTIONAL CHARACTERISTICS OF MICROGLIA IN THE POSTNATAL RAT STRIATUM

M V Antipova; V V Guselnikova; D E Korzhevskii

Medical academic journal ›› 2019, Vol. 19 ›› Issue (1S) :133 -134.

Articles

oration

STRUCTURAL AND FUNCTIONAL CHARACTERISTICS OF MICROGLIA IN THE POSTNATAL RAT STRIATUM

Author information +

History +

Abstract

The aim of this study was to evaluate the morphological and functional characteristics of microglial cells in the rat striatum at different stages of postnatal development. Using immunocytochemical methods and fluorescent microscopy, brain sections were analysed at each of the following postnatal ages: day 7 (n = 4), day 14 (n = 3), 4 to 6 months (n = 3). Different morphological and functional types of microglial cells were identified and characterized in details. It was noted that microglia activated during normal brain development do not contain vimentin, which is characteristic of stroke-activated microglia.

Keywords

microglia / striatum / postnatal development / Iba-1 / vimentin / Iba-1

Cite this article

Download citation ▾

M V Antipova, V V Guselnikova, D E Korzhevskii. STRUCTURAL AND FUNCTIONAL CHARACTERISTICS OF MICROGLIA IN THE POSTNATAL RAT STRIATUM. Medical academic journal, 2019, 19(1S): 133-134 DOI:

登录浏览全文

4963

注册一个新账户忘记密码

References

Publishing order | Descend order by publishing year | Descend order by cited within

[1]	Wolf SA, Boddeke HW, Kettenmann H. Microglia in Physiology and Disease. Annual Review of Physio¬logy. 2017;79(1):619-643.

[2]	Wilhelmsson U, Andersson D, de Pablo Y, et al. Injury leads to the appearance of cells with characteristics of both microglia and astrocytes in mouse and human brain. Cereb Cortex. 2017;6:3360-3377.