ANTIMICROBIAL ACTIVITY OF LYSOZYME TOWARDS LISTERIA MONOCYTOGENES AT VARIOUS MEDIUM CONDITIONS

M N Berlov; S V Legkovoy; E S Umnyakova; V N Kokryakov

Medical academic journal ›› 2019, Vol. 19 ›› Issue (1S) :161 -162.

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ANTIMICROBIAL ACTIVITY OF LYSOZYME TOWARDS LISTERIA MONOCYTOGENES AT VARIOUS MEDIUM CONDITIONS

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Abstract

The in vitro antimicrobial action of human leukocyte lysozyme from on gram-positive bacterium Listeria monocytogenes under various medium conditions was studied. It was shown that in a low ionic strength buffer (without NaCl), lower doses of lysozyme are required to reveal the microbicidal effect than in the case of 0.075 or 0.15 M NaCl. The bacterial growth phase does not significantly affect the antimicrobial activity of lysozyme. The results obtained are consistent with the two-stage mechanism of the antimicrobial action of lysozyme, which includes enzymatic and non-enzymatic action.

Keywords

Listeria monocytogenes / lysozyme / antimicrobial activity / Listeria monocytogenes

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M N Berlov, S V Legkovoy, E S Umnyakova, V N Kokryakov. ANTIMICROBIAL ACTIVITY OF LYSOZYME TOWARDS LISTERIA MONOCYTOGENES AT VARIOUS MEDIUM CONDITIONS. Medical academic journal, 2019, 19(1S): 161-162 DOI:

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References

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