Preparations of the nitrofuran series have high antibacterial activity, have an effect on antibiotic-resistant and sulfamid-resistant bacterial strains, and have a pronounced synergism with antibiotics [1, 2].

According to our data, neoplasms of the bladder account for 8% of all urological diseases. The overwhelming majority of patients are people over 50 years old; men get sick more often than women (5: 1).

Despite the introduction into clinical practice of a number of new methods in the treatment of peritonitis (peritoneal dialysis, new antibiotics, hypothermia, etc.), the mortality rate in this disease, which is widespread in urgent surgery, remains high - 35% or more.

The main direction of the development of epidemiological research in oncology should be considered the clarification of the characteristics of the spread of malignant neoplasms in various territories of the country, in various ethnic, professional and other groups of the population; isolation and study of high-risk groups, in particular patients with precancerous diseases; determination of the role of chemical, physical and biological factors in the occurrence of human tumors; study of possible pathogenetic links between malignant neoplasms and other diseases, mainly chronic (gastritis, bronchitis, tuberculosis, diabetes, etc.); study of the causes of changes (decrease or increase) in the levels of morbidity, mortality from certain forms of malignant tumors; assessment of the effectiveness of preventive measures, etc.