In the pathogenesis of rheumatism, like a number of other diseases with an allergic component, it is possible to assume a change in the function of the pituitary-adrenal system.
Most scientists are supporters of the infectious-allergic nature of rheumatism (A.I. Nesterov, V.I. Molchanov, V.E. Nezlin, V.I. Ioffe, M.P. Konchalovsky, etc.). A number of authors indicate that focal ß-streptococcal infection is a source of body sensitization necessary for the onset of the disease.
Work on blood preservation and experimental biochemical studies show that the usefulness of erythrocytes is associated with the normal course of the metabolic process in them, mainly manifested in glycolysis, which gives erythrocytes all the energy necessary for metabolism. SE Severin (1946), GE Vladimirov and others (1947) note that the termination of glycolysis leads to hemolysis and death of erythrocytes.
A number of authors (Edene, 1936; Kolbing, 1950; Chonicher, Szabo, 1955) indicate that the use of a lantoside test can, to some extent, substantiate the diagnosis of an active rheumatic process.
In recent years, among the effective antirheumatic agents, combined preparations consisting of pyramidone and butadiene, which include reopyrin, are mentioned.
In recent years, mainly mild forms of dysentery have been observed. Their diagnosis and differential diagnosis from other acute intestinal diseases are often very difficult.
P., 63 years old, delivered on 12/1 1962 in a grave, unconscious state. Scanty anamnestic information was obtained from a flatmate.