Hypertension and Alzheimer’s disease

Abstract

Alzheimer’s disease (AD) accounts for 60% to 80% of dementia cases and is the most common cause of dementia. In the past decade, studies have shown a close association between blood pressure and AD. It is found that elevated blood pressure at midlife would increase the risk of dementia, including AD. However, there is no definitive conclusion about the relationship between elderly blood pressure and cognitive function. Abnormal pulse pressure may also increase the risk of dementia. The impact of antihypertensive drugs is inconclusive, and the mechanism of their protection of cognitive function is not clear.

Keywords

hypertension / Alzheimer’s disease (AD) / risk factor / treatment / high blood pressure / hypotension / antihypertensive drugs