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A CRISPR activation screen identifies genes that enhance SARS-CoV-2 infection

  • Fei Feng 1 ,
  • Yunkai Zhu 1 ,
  • Yanlong Ma 1 ,
  • Yuyan Wang 1 ,
  • Yin Yu 1 ,
  • Xinran Sun 1 ,
  • Yuanlin Song 2 ,
  • Zhugui Shao 3 ,
  • Xinxin Huang 4 ,
  • Ying Liao 5 ,
  • Jingyun Ma 6 ,
  • Yuping He 7 ,
  • Mingyuan Wang 8 ,
  • Longhai Tang 8 ,
  • Yaowei Huang 9 ,
  • Jincun Zhao ,
  • Qiang Ding ,
  • Youhua Xie 1 ,
  • Qiliang Cai 1 ,
  • Hui Xiao 3 ,
  • Chun Li , 2 ,
  • Zhenghong Yuan , 1 ,
  • Rong Zhang , 1
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  • 1. Key Laboratory of Medical Molecular Virology(MOE/NHC/CAMS), School of Basic Medical Sciences, Shanghai Medical College, Shanghai Institute of Infectious Disease and Biosecurity, Fudan University, Shanghai 200032, China
  • 2. Department of Pulmonary Medicine, Zhongshan Hospital, Shanghai Key Laboratory of Lung Inflammation and Injury, Fudan University, Shanghai 200032, China
  • 3. The Center for Microbes, Development and Health, CAS Key Laboratory of Molecular Virology & Institute Pasteur of Shanghai, CAS Center for Excellence in Molecular Cell Science, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai 200031, China
  • 4. Technical Center for Animal, Plant and Food Inspection and Quarantine of Shanghai Customs, Shanghai 200032, China
  • 5. Shanghai Veterinary Research Institute, CAAS, Shanghai 200241, China
  • 6. College of Animal Science, South China Agricultural University, Guangzhou 510642, China
  • 7. Shanghai International Travel Healthcare Center, Shanghai 200335, China
  • 8. Suzhou Blood Center, Suzhou 215006, China
  • 9. Key Laboratory of Animal Virology of Ministry of Agriculture, College of Animal Sciences, Zhejiang University, Hangzhou 310058, China 10 State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou 510182, China 11 Center for Infectious Disease Research, School of Medicine, Tsinghua University, Beijing 100086, China

Accepted date: 28 Jul 2022

Copyright

2022 The Author(s) 2022. Published by Oxford University Press on behalf of Higher Education Press.

Cite this article

Fei Feng , Yunkai Zhu , Yanlong Ma , Yuyan Wang , Yin Yu , Xinran Sun , Yuanlin Song , Zhugui Shao , Xinxin Huang , Ying Liao , Jingyun Ma , Yuping He , Mingyuan Wang , Longhai Tang , Yaowei Huang , Jincun Zhao , Qiang Ding , Youhua Xie , Qiliang Cai , Hui Xiao , Chun Li , Zhenghong Yuan , Rong Zhang . A CRISPR activation screen identifies genes that enhance SARS-CoV-2 infection[J]. Protein & Cell, 2023 , 14(1) : 64 -68 . DOI: 10.1093/procel/pwac036

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