BMAL1 functions as a cAMP-responsive coactivator of HDAC5 to regulate hepatic gluconeogenesis
Published date: 29 Nov 2018
Copyright
Jian Li , Sihan Lv , Xinchen Qiu , Jiamin Yu , Junkun Jiang , Yalan Jin , Wenxuan Guo , Ruowei Zhao , Zhen-Ning Zhang , Chao Zhang , Bing Luan . BMAL1 functions as a cAMP-responsive coactivator of HDAC5 to regulate hepatic gluconeogenesis[J]. Protein & Cell, 2018 , 9(11) : 976 -980 . DOI: 10.1007/s13238-018-0514-y
| 1 |
Altarejos JY, Montminy M (2011) CREB and the CRTC co-activators: sensors for hormonal and metabolic signals. Nat Rev Mol Cell Biol 12:141–151
|
| 2 |
Gross DN, Wan M, Birnbaum MJ (2009) The role of FOXO in the regulation of metabolism. Curr Diabetes Rep 9:208–214
|
| 3 |
Lan MS, Wang HW, Chong J, Breslin MB (2007) Coupling of glucose response element from L-type pyruvate kinase and G6Pase promoter enhances glucose responsive activity in hepatoma cells. Mol Cell Biochem 300:191–196
|
| 4 |
Liu Y, Dentin R, Chen D, Hedrick S, Ravnskjaer K, Schenk S, Milne J, Meyers DJ, Cole P, Yates J 3rd, Olefsky J, Guarente L, Montminy M (2008) A fasting inducible switch modulates gluconeogenesis via activator/coactivator exchange. Nature 456:269–273
|
| 5 |
Lv S, Qiu X, Li J, Li W, Zhang C, Zhang ZN, Luan B (2016) Suppression of CRTC2-mediated hepatic gluconeogenesis by TRAF6 contributes to hypoglycemia in septic shock. Cell Discov 2:16046
|
| 6 |
Lv S, Qiu X, Li J, Liang J, Li W, Zhang C, Zhang ZN, Luan B (2017) Glucagon-induced extracellular cAMP regulates hepatic lipid metabolism. J Endocrinol 234:73–87
|
| 7 |
Marcheva B, Ramsey KM, Buhr ED, Kobayashi Y, Su H, Ko CH, Ivanova G, Omura C, Mo S, Vitaterna MH, Lopez JP, Philipson LH, Bradfield CA, Crosby SD, JeBailey L, Wang X, Takahashi JS, Bass J (2010) Disruption of the clock components CLOCK and BMAL1 leads to hypoinsulinaemia and diabetes. Nature 466:627–631
|
| 8 |
Mihaylova MM, Vasquez DS, Ravnskjaer K, Denechaud PD, Yu RT, Alvarez JG, Downes M, Evans RM, Montminy M, Shaw RJ (2011) Class IIa histone deacetylases are hormone-activated regulators of FOXO and mammalian glucose homeostasis. Cell 145:607–621
|
| 9 |
Montminy M (1997) Transcriptional regulation by cyclic AMP. Annu Rev Biochem 66:807–822
|
| 10 |
Pearson RB, Kemp BE (1991) Protein kinase phosphorylation site sequences and consensus specificity motifs: tabulations. Methods Enzymol 200:62–81
|
| 11 |
Qiu X, Li J, Lv S, Yu J, Jiang J, Yao J, Xiao Y,Xu B, He H, Guo F, Zhang ZN, Zhang C, Luan B (2017) HDAC5 integrates ER stress and fasting signals to regulate hepatic fatty acid oxidation. J Lipid Res 59(2):330–338
|
| 12 |
Reppert SM, Weaver DR (2002) Coordination of circadian timing in mammals. Nature 418:935–941
|
| 13 |
Rudic RD, McNamara P, Curtis AM, Boston RC, Panda S, Hogenesch JB, Fitzgerald GA (2004) BMAL1 and CLOCK, two essential components of the circadian clock, are involved in glucose homeostasis. PLoS Biol 2:e377
|
| 14 |
Vollmers C, Gill S, DiTacchio L, Pulivarthy SR, Le HD, Panda S (2009) Time of feeding and the intrinsic circadian clock drive rhythms in hepatic gene expression. Proc Natl Acad Sci USA 106:21453–21458
|
| 15 |
Wang B, Moya N, Niessen S, Hoover H, Mihaylova MM,Shaw RJ , Yates JR 3rd, Fischer WH, Thomas JB, Montminy M (2011) A hormone-dependent module regulating energy balance. Cell 145:596–606
|
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