Association between exposure to particulate matter during pregnancy and birthweight: a systematic review and a meta-analysis of birth cohort studies

Abstract

Studies of the associations between maternal exposure to particulate matter (PM) and risk of adverse effects on fetal growth are inconsistent and inconclusive. This question can be well answered by carefully designed birth cohort studies; however, so far the evidence from such studies has not come to the same conclusion. We sought to evaluate the association between maternal exposures to PM and low birthweight (LBW) enrolling 14 studies from 11 centers, and to explore the influence of trimester and exposure assessment methods on between-center heterogeneity in this association. Data were derived from PubMed, Embase, Google Scholar, CNKI, and WanFang database, references from relevant articles, and results from published studies until March 2017. Using a random-effects meta-analysis, we combined the coefficient and odds ratios (OR) of individual studies conducted among 14 birth cohort studies. Random-effect meta-analysis results suggested that a 17% and 6% increase in risk of LBW was relevant to a 10 mg/m³ rise in PM_2.5 and PM₁₀ exposure concentrations at the 3rd trimester (pooled odds ratios (OR), 1.17 and 1.06; 95% confidence interval (CI), 0.94–1.46 and 0.97-1.15, respectively), but the null value was included in our 95% CI. Our results showed that exposure to PM_2.5 and PM₁₀ during pregnancy has a positive relevance to LBW based on birth cohort studies. However, neither reached formal statistical significance. Negative impacts on outcomes of birth is implied by maternal exposure to PM. Further mechanistic researches are needed to explain the connection between PM pollution and LBW.

References

[1] Jacobs M, Zhang G, Chen S, The association between ambient air pollution and selected adverse pregnancy outcomes in China: A systematic review[J]. Sci Total Environ, 2017, 579: 1179–1192

[2] Dehbi HM, Blangiardo M, Gulliver J, Air pollution and cardiovascular mortality with over 25 years follow-up: A combined analysis of two British cohorts[J]. Environ Int, 2017, 99: 275–281

[3] Fajersztajn L, Saldiva P, Pereira LA, Short-term effects of fine particulate matter pollution on daily health events in Latin America: a systematic review and meta-analysis[J]. Int J Public Health, 2017, March 2

[4] Hao Y, Zhang G, Han B, Prospective evaluation of respiratory health benefits from reduced exposure to airborne particulate matter[J]. Int J Environ Health Res, 2017, 27(2): 126–135

[5] Ha EH, Lee BE, Park HS, Prenatal exposure to PM10 and preterm birth between 1998 and 2000 in Seoul, Korea[J]. J Prev Med Public Health, 2004, 37(4): 300–305

[6] Stieb DM, Chen L, Eshoul M, Ambient air pollution, birth weight and preterm birth: a systematic review and meta-analysis[J]. Environ Res, 2012, 117: 100–111

[7] Giovannini N, Schwartz L, Cipriani S, Particulate matter (PM10) exposure, birth and fetal-placental weight and umbilical arterial pH: results from a prospective study[J]. J Matern Fetal Neonatal Med, 2017, April 10: 1–5

[8] Malley CS, Kuylenstierna JC, Vallack HW, Preterm birth associated with maternal fine particulate matter exposure: A global, regional and national assessment[J]. Environ Int, 2017, 101: 173–182

[9] Qian Z, Liang S, Yang S, Ambient air pollution and preterm birth: A prospective birth cohort study in Wuhan, China[J]. Int J Hyg Environ Health, 2016, 219(2): 195–203

[10] Stieb DM, Chen L, Beckerman BS, Associations of pregnancy outcomes and PM2.5 in a national Canadian study[J]. Environ Health Perspect, 2016, 124(2): 243–249

[11] Den Dekker HT, Sonnenschein-van der Voort AM, de Jongste JC, Early growth characteristics and the risk of reduced lung function and asthma: A meta-analysis of 25,000 children[J]. J Allergy Clin Immunol, 2016, 137(4): 1026–1035

[12] Goisis A, Özcan B, Myrskylä M. Decline in the negative association between low birth weight and cognitive ability[J]. Proc Natl Acad Sci U S A, 2017, 114(1): 84–88

[13] Raaijmakers A, Zhang ZY, Claessens J, Does extremely low birth weight predispose to low-renin hypertension[J]? Hypertension, 2017, 69(3): 443–449

[14] Laurent O, Hu J, Li L, Low birth weight and air pollution in California: Which sources and components drive the risk[J]? Environ Int, 2016, 92-93: 471–477

[15] Stieb DM, Chen L, Hystad P, A national study of the association between traffic-related air pollution and adverse pregnancy outcomes in Canada, 1999-2008[J]. Environ Res, 2016, 148: 513–526

[16] Hao Y, Strosnider H, Balluz L,Geographic variation in the association between ambient fine particulate matter (PM2.5) and term low birth weight in the United States[J]. Environ Health Perspect, 2016, 124(2): 250–255

[17] Leem JH, Kaplan BM, Shim YK, Exposures to air pollutants during pregnancy and preterm delivery[J]. Environ Health Perspect, 2006, 114(6): 905–910

[18] Pedersen M, Giorgis-Allemand L, Bernard C, Ambient air pollution and low birthweight: a European cohort study (ESCAPE)[J]. Lancet Respir Med, 2013, 1(9): 695–704

[19] Deeks JJ, Higgins JPT, Altman DG. Analysing Data and Undertaking Meta-Analyses. Cochrane Handbook for Systematic Reviews of Interventions: John Wiley & Sons, Ltd[J], 2008:243–296.

[20] Zhu X, Liu Y, Chen Y, Maternal exposure to fine particulate matter (PM2.5) and pregnancy outcomes: a meta-analysis[J]. Environ Sci Pollut Res Int, 2015, 22(5): 3383–3396

[21] Dadvand P, Parker J, Bell ML, Maternal exposure to particulate air pollution and term birth weight: a multi-country evaluation of effect and heterogeneity[J]. Environ Health Perspect, 2013, 121(3): 367–373

[22] Wang J, Zhang D, Huang R, Gamma-glutamyltransferase and risk of cardiovascular mortality: A dose-response meta-analysis of prospective cohort studies[J]. PLoS One, 2017, 12(2): e0172631

[23] Wells GA, Shea BJ, O'Connell D, Peterson J, Welch V, Losos M, The Newcastle–Ottawa Scale (NOS) for Assessing the Quality of Non-Randomized Studies in Meta-Analysis[J]. Applied Engineering in Agriculture 2014; 18: págs. 727–734.

[24] Brauer M, Lencar C, Tamburic L, A cohort study of traffic-related air pollution impacts on birth outcomes[J]. Environ Health Perspect, 2008, 116(5): 680–686

[25] Hannam K, McNamee R, Baker P, Air pollution exposure and adverse pregnancy outcomes in a large UK birth cohort: use of a novel spatio-temporal modelling technique[J]. Scand J Work Environ Health, 2014, 40(5): 518–530

[26] Gehring U, Tamburic L, Sbihi H, Impact of noise and air pollution on pregnancy outcomes[J]. Epidemiology, 2014, 25(3): 351–358

[27] Araban M, Kariman N, Tavafian SS, Air pollution and low birth weight: a historical cohort study from Tehran[J]. East Mediterr Health J, 2012, 18(6): 556–560

[28] van den Hooven EH, Pierik FH, de Kluizenaar Y, Air pollution exposure during pregnancy, ultrasound measures of fetal growth, and adverse birth outcomes: a prospective cohort study[J]. Environ Health Perspect, 2012, 120(1): 150–156

[29] Salam MT, Millstein J, Li YF, Birth outcomes and prenatal exposure to ozone, carbon monoxide, and particulate matter: results from the Children’s Health Study[J]. Environ Health Perspect, 2005, 113(11): 1638–1644

[30] Ha S, Hu H, Roussos-Ross D, The effects of air pollution on adverse birth outcomes[J]. Environ Res, 2014, 134: 198–204

[31] Dibben C, Clemens T. Place of work and residential exposure to ambient air pollution and birth outcomes in Scotland, using geographically fine pollution climate mapping estimates. Environ Res, 2015, 140: 535–541

[32] Dadvand P, Ostro B, Figueras F, Residential proximity to major roads and term low birth weight: the roles of air pollution, heat, noise, and road-adjacent trees. Epidemiology, 2014, 25(4): 518–525

[33] Poirier A, Dodds L, Dummer T, Maternal exposure to air pollution and adverse birth outcomes in Halifax, Nova Scotia[J]. J Occup Environ Med, 2015, 57(12): 1291–1298

[34] Lin CM, Li CY, Yang GY, Association between maternal exposure to elevated ambient sulfur dioxide during pregnancy and term low birth weight[J]. Environ Res, 2004, 96(1): 41–50

[35] Dugandzic R, Dodds L, Stieb D, The association between low level exposures to ambient air pollution and term low birth weight: a retrospective cohort study[J]. Environ Health, 2006, 5(1): 3

[36] Xu X, Sharma RK, Talbott EO, PM10 air pollution exposure during pregnancy and term low birth weight in Allegheny County, PA, 1994-2000[J]. Int Arch Occup Environ Health, 2011, 84(3): 251–257

[37] Kim OJ, Ha EH, Kim BM, PM10 and pregnancy outcomes: a hospital-based cohort study of pregnant women in Seoul[J]. J Occup Environ Med, 2007, 49(12): 1394–1402

[38] Cândido da Silva AM, Moi GP, Mattos IE, Low birth weight at term and the presence of fine particulate matter and carbon monoxide in the Brazilian Amazon: a population-based retrospective cohort study[J]. BMC Pregnancy Childbirth, 2014, 14: 309

[39] Sapkota A, Chelikowsky AP, Nachman KE, Exposure to particulate matter and adverse birth outcomes: a comprehensive review and meta-analysis[J]. Air Qual Atmos Health, 2012, 5(4):369–381.

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2017 2017 by the Journal of Biomedical Research.