Development of ABE and AKBE base editors in watermelon

Acknowledgements

We thank Dr Huanbin Zhou for his technical advisement and support. This work was supported by the Key Program of the National Natural Science Foundation of China (U23A20208), the National Youth Talent Program (A279021801), the National Key Research and Development Program of China (2023YFE0206900), the National Natural Science Foundation of China (32372734), Luoyang Major Science and Technology Tackling Key Issues Project (Public Announcement and Leadership, 2301024A), Earmarked Fund for China Agriculture Research System (CARS-25), Key-Area R&D Program of Guangdong Province (2022B0202060001), Key R&D Program of Shaanxi Province (2023-YBNY-008, 2024NC-YBXM-032), and the Natural Science Foundation of Shaanxi Province (2022JM-112).

Author contributions

L.Y., F.L., and X.Z. conceived the study. D.W., T.Z., C.L., Y.C., S.T. C.T., P.G., S.L., M.L., and J.W. executed the experiments. L.Y. and D.W. wrote the manuscript.

Data availability

The plasmid used in this study will be available at Addgene, and the supplementary vector sequences, primers, and methods generated during this study are available in the Figshare database under the accession https://figshare.com/s/c314f1eb66982d91bbea. The additional data related to this paper may be requested from the authors.

Conflict of interest statement

The authors declare no competing financial interests.

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