Increased artemisinin production by promoting glandular secretory trichome formation and reconstructing the artemisinin biosynthetic pathway in Artemisia annua

Acknowledgements

This work was supported by National Key R&D Program of China (2018YFA0900600), the Bill & Melinda Gates Foundation (OPP1199872 and INV-027291), the China Postdoctoral Science Foundation (2022M722851), the National Natural Science Foundation of China (82274047, 31770327, 32070329, 82003889), SJTU Trans-med Awards Research (20190104), SJTU Global Strategic Partnership Fund (2020 SJTU-CORNELL), Zhejiang Provincial Natural Science Foundation of China (LQ21H280004), National Young Qihuang Scholars Training Program, and the National ‘Ten-thousand Talents Program’ for Leading Talents of Science and Technology Innovation in China.

Author contributions

Y.L. and K.T. designed the research. Y.L., W.Q., H.L., T.C., X.Y., W.H., B.P., and J.S. performed most of the experiments. Y.L. drafted the manuscript. Y.L., W.Q., X.F., L.L., X.H., G.K., and K.T. revised the manuscript. All authors have approved the manuscript.

Data availability

All data supporting this study are available in the article.

Conflict of interest

The authors declare no conflicts of interest.

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