%A Jonas OGIEN, Anthony DAURES, Maxime CAZALAS, Jean-Luc PERROT, Arnaud DUBOIS %T Line-field confocal optical coherence tomography for three-dimensional skin imaging %0 Journal Article %D 2020 %J Front. Optoelectron. %J Frontiers of Optoelectronics %@ 2095-2759 %R 10.1007/s12200-020-1096-x %P 381-392 %V 13 %N 4 %U {https://journal.hep.com.cn/foe/EN/10.1007/s12200-020-1096-x %8 2020-12-15 %X

This paper reports on the latest advances in line-field confocal optical coherence tomography (LC-OCT), a recently invented imaging technology that now allows the generation of either horizontal (x× y) section images at an adjustable depth or vertical (x× z) section images at an adjustable lateral position, as well as three-dimensional images. For both two-dimensional imaging modes, images are acquired in real-time, with real-time control of the depth and lateral positions. Three-dimensional (x× y× z) images are acquired from a stack of horizontal section images. The device is in the form of a portable probe. The handle of the probe has a button and a scroll wheel allowing the user to control the imaging modes. Using a supercontinuum laser as a broadband light source and a high numerical microscope objective, an isotropic spatial resolution of ~1 mm is achieved. The field of view of the three-dimensional images is 1.2 mm × 0.5 mm × 0.5 mm (x× y× z). Images of skin tissues are presented to demonstrate the potential of the technology in dermatology.