Comprehensive treatment of acute-on-chronic liver failure in a patient with hepatitis B: a case report

Abstract

The clinical data of a patient with acute-on-chronic liver failure were analyzed retrospectively. The patient has suffered from hepatitis B for 30 years. His liver function deteriorated, yielding Child-Pugh grade C and reaching a model for end-stage liver disease score of 33 points within a short period; this condition was complicated with highly active variceal bleeding and coagulation system failure (PT > 100 s). The patient also presented hepatocellular carcinoma. Comprehensive treatments included effective inhibition of hepatitis B virus replication and intensive care support. Piggyback orthotopic liver transplantation was performed as the final treatment. The patient recovered uneventfully and was discharged after surgery.

Keywords

acute-on-chronic liver failure / submassive necrosis / viral hepatitis B / esophageal variceal bleeding / liver transplantation

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版权

2014 Higher Education Press and Springer-Verlag Berlin Heidelberg