Effect of Feixian Recipe on laminin, collagen I and III in rats with pulmonary fibrosis induced by bleomycin

Frontiers of Medicine ›› 2008, Vol. 2 ›› Issue (3) : 314-316.

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PDF(69 KB)
Frontiers of Medicine ›› 2008, Vol. 2 ›› Issue (3) : 314-316. DOI: 10.1007/s11684-008-0060-8

Effect of Feixian Recipe on laminin, collagen I and III in rats with pulmonary fibrosis induced by bleomycin

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Effect of Feixian Recipe on laminin, collagen I and III in rats with pulmonary fibrosis induced by bleomycin

  • ZHANG Xiaomei1, JIANG Liangduo2, ZHANG Wei2, WU Jianjun3, LU Xiangfeng4
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Abstract

The aim of this paper is to observe the effect of the Feixian Recipe on pulmonary fibrosis in rats. A rat model with pulmonary fibrosis was established by intratracheal injection of bleomycin. On days 14, 28 and 45, the contents of laminin, collagen I and collagen III in lung tissue homogenate in the model group, the sham operated group, the Feixian group and the prednisone group were measured. The contents of laminin and collagen I and III were decreased significantly by the Feixian Recipe. Feixian Recipe has a significant therapeutic effect on bleomycin-induced pulmonary fibrosis in rats.

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. Effect of Feixian Recipe on laminin, collagen I and III in rats with pulmonary fibrosis induced by bleomycin. Frontiers of Medicine. 2008, 2(3): 314-316 https://doi.org/10.1007/s11684-008-0060-8

参考文献

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