Inhibition of protein kinase B by Palmitate in the insulin signaling of HepG2 cells and the preventive effect of Arachidonic acid on insulin resistance

Frontiers of Medicine ›› 2007, Vol. 1 ›› Issue (2) : 200-206.

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Frontiers of Medicine ›› 2007, Vol. 1 ›› Issue (2) : 200-206. DOI: 10.1007/s11684-007-0038-y

Inhibition of protein kinase B by Palmitate in the insulin signaling of HepG2 cells and the preventive effect of Arachidonic acid on insulin resistance

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Inhibition of protein kinase B by Palmitate in the insulin signaling of HepG2 cells and the preventive effect of Arachidonic acid on insulin resistance

  • XIA Yanzhi1, WAN Xuedong2, DUAN Qiuhong2, HE Shansu2, WANG Ximing2
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Abstract

Elevated plasma levels of free fatty acids (FFAs) may contribute to insulin resistance (IR) that is characteristic of type 2 diabetes mellitus. In this study, we investigated the effects of two fatty acids, palmitate (PA) and arach

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. Inhibition of protein kinase B by Palmitate in the insulin signaling of HepG2 cells and the preventive effect of Arachidonic acid on insulin resistance. Frontiers of Medicine. 2007, 1(2): 200-206 https://doi.org/10.1007/s11684-007-0038-y

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