Deciphering the molecular and physiological connections between obesity and breast cancer
Received date: 07 Jan 2011
Accepted date: 14 Feb 2011
Published date: 01 Jun 2011
Copyright
Obesity is associated with the higher risk of breast cancer in postmenopausal women. The leptin signaling pathway is recognized to primarily regulate energy balance and associated with breast cancer. Furthermore, the estrogen signaling pathway plays a critical role in breast carcinogenesis. In this review, we discuss how obesity is linked to breast cancer via cross-talk of leptin and estrogen pathways.
Zhao HE , Andy B. CHEN , Gen-Sheng FENG . Deciphering the molecular and physiological connections between obesity and breast cancer[J]. Frontiers in Biology, 2011 , 6(3) : 206 -212 . DOI: 10.1007/s11515-011-1138-2
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