%A Suying Xu, Adam C. Sedgwick, Souad A. Elfeky, Wenbo Chen, Ashley S. Jones, George T. Williams, A. Toby A. Jenkins, Steven D. Bull, John S. Fossey, Tony D. James %T A boronic acid-based fluorescent hydrogel for monosaccharide detection %0 Journal Article %D 2020 %J Front. Chem. Sci. Eng. %J Frontiers of Chemical Science and Engineering %@ 2095-0179 %R 10.1007/s11705-019-1812-5 %P 112-116 %V 14 %N 1 %U {https://journal.hep.com.cn/fcse/EN/10.1007/s11705-019-1812-5 %8 2020-02-15 %X

A boronic acid-based anthracene fluorescent probe was functionalised with an acrylamide unit to incorporate into a hydrogel system for monosaccharide detection. In solution, the fluorescent probe displayed a strong fluorescence turn-on response upon exposure to fructose, and an expected trend in apparent binding constants, as judged by a fluorescence response where D-fructose>D-galactose>D-mannose>D-glucose. The hydrogel incorporating the boronic acid monomer demonstrated the ability to detect monosaccharides by fluorescence with the same overall trend as the monomer in solution with the addition of D-fructose resulting in a 10-fold enhancement (≤0.25 mol/L).