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Microwave-assisted synthesis and antimicrobial activities of 2-aryl-3-(naphthalene-1 or 2-yl)-1,3-thiazolidin-4-ones
Received date: 28 Oct 2008
Accepted date: 29 Nov 2008
Published date: 05 Jun 2009
Copyright
2-aryl-3-(naphthalene-1 or 2-yl)-1,3-thiazolidin-4-ones 4 and 5 were synthesized in 41%-67% yield by using microwave-assisted one-pot protocol. The structures of the new compounds 4l, 4m, 5c, 5e, 5g, 5h, and 5j-5m were confirmed by IR, NMR, MS, and elemental analysis. The antimicrobial activities of the compounds against Pseudomonas syringae pv. lachrymans (Smith et Bryan) Young, Dye & Wilkie, Botrytis cinerea Pers., and Sphaerotheca fusca Blum. were examined. Some of the compounds showed good antifungical activity against Sphaerotheca fusca Blum.
Key words： microwave-assisted synthesis; naphthyl; thiazolidin-4-one; antimicrobial
Hua CHEN , Yanan LI , Jie BAI , Lian ZHAO , Xiangguo YUAN , Xiaoliu LI , Keqiang CAO . Microwave-assisted synthesis and antimicrobial activities of 2-aryl-3-(naphthalene-1 or 2-yl)-1,3-thiazolidin-4-ones[J]. Frontiers of Chemical Science and Engineering, 2009 , 3(2) : 186 -191 . DOI: 10.1007/s11705-009-0004-0
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