World’s top 50 high-impact research studies in traditional medicine in 2024

参考文献

[[1]] Bao C, Wu L, Wang D, et al. Acupuncture improves the symptoms, intestinal microbiota, and inflammation of patients with mild to moderate Crohn’s disease: a randomized controlled trial. EClinicalMedicine. 2022;45:101300.

[[2]] Yin X, Li W, Liang T, et al. Effect of electroacupuncture on insomnia in patients with depression: a randomized clinical trial. JAMA Netw Open. 2022;5(7):e2220563.

[[3]] Fan JQ, Lu WJ, Tan WQ, et al. Effectiveness of acupuncture for anxiety among patients with Parkinson disease: a randomized clinical trial. JAMA Netw Open. 2022;5(9):e2232133.

[[4]] Zhao J, Tostivint I, Xu L, et al. Efficacy of combined Abelmoschus manihot and Irbesartan for reduction of albuminuria in patients with type 2 diabetes and diabetic kidney disease: a multicenter randomized double-blind parallel controlled clinical trial. Diabetes Care. 2022;45(7):e113-e115.

[[5]] Zhu Y, Wang F, Zhou J, et al. Effect of acupoint hot compress on postpartum urinary retention after vaginal delivery: a randomized clinical trial. JAMA Netw Open. 2022;5(5):e2213261.

[[6]] Usichenko TI, Henkel BJ, Klausenitz C, et al. Effectiveness of acupuncture for pain control after cesarean delivery: a randomized clinical trial. JAMA Netw Open. 2022;5(2):e220517.

[[7]] Ji D, Chen Y, Bi J, et al. Entecavir plus Biejia-Ruangan compound reduces the risk of hepatocellular carcinoma in Chinese patients with chronic hepatitis B. [J] Hepatol. 2022;77(6):1515-1524.

[[8]] Wang W, Liu Y, Yang X, et al. Effects of electroacupuncture for opioid-induced constipation in patients with cancer in China: a randomized clinical trial. JAMA Netw Open. 2023;6(2):e230310.

[[9]] Hershman DL, Unger JM, Greenlee H, et al. Comparison of acupuncture vs sham acupuncture or waiting list control in the treatment of aromatase inhibitor-related joint pain: a randomized clinical trial. JAMA Netw Open. 2022;5(11):e2241720.

[[10]] Zheng H, Gao T, Zheng QH, et al. Acupuncture for patients with chronic tension-type headache: a randomized controlled trial. Neurology. 2022;99(14):e1560-e1569.

[[11]] Yin S, Jin W, Qiu Y, et al. Solamargine induces hepatocellular carcinoma cell apoptosis and autophagy via inhibiting LIF/miR-192-5p/CYR61/Akt signaling pathways and eliciting immunostimulatory tumor microenvironment. [J] Hematol Oncol. 2022;15(1):32.

[[12]] Wang Y, Wang X, Li Y, et al. Xuanfei Baidu decoction reduces acute lung injury by regulating infiltration of neutrophils and macrophages via PD-1/IL17A pathway. Pharmacol Res. 2022;176:106083.

[[13]] Li H, Zhao X, Zheng L, et al. Bruceine A protects against diabetic kidney disease via inhibiting galectin-1. Kidney Int. 2022;102(3):521-535.

[[14]] Wang TH, Tseng WC, Leu YL, et al. The flavonoid corylin exhibits lifespan extension properties in mouse. Nat Commun. 2022;13(1):1238.

[[15]] Guo B, Zhao C, Zhang C, et al. Elucidation of the anti-inflammatory mechanism of Er Miao San by integrative approach of network pharmacology and experimental verification. Pharmacol Res. 2022;175:106000.

[[16]] Zhang ZW, Gao CS, Zhang H, et al.Morinda officinalis oligosaccharides increase serotonin in the brain and ameliorate depression via promoting 5-hydroxytryptophan production in the gut microbiota. Acta Pharm Sin B. 2022;12(8):3298-3312.

[[17]] Wang F, Jin S, Mayca Pozo F, et al.Chemical screen identifies shikonin as a broad DNA damage response inhibitor that enhances chemotherapy through inhibiting ATM and ATR. Acta Pharm Sin B. 2022;12(3):1339-1350.

[[18]] Li Z, Pan H, Yang J, et al. Xuanfei Baidu formula alleviates impaired mitochondrial dynamics and activated NLRP3 inflammasome by repressing NF-κB and MAPK pathways in LPS-induced ALI and inflammation models. Phytomedicine. 2023;108:154545.

[[19]] Zhou X, Zhao S, Liu T, et al.Schisandrol A protects AGEs-induced neuronal cells death by allosterically targeting ATP6V0d1 subunit of V-ATPase. Acta Pharm Sin B. 2022;12(10):3843-3860.

[[20]] Liao M, Xie Q, Zhao Y, et al.Main active components of Si-Miao-Yong-An decoction (SMYAD) attenuate autophagy and apoptosis via the PDE5A-AKT and TLR4-NOX4 pathways in isoproterenol (ISO)-induced heart failure models. Pharmacol Res. 2022;176:106077.

[[21]] Leong W, Huang G, Liao W, et al. Traditional Patchouli essential oil modulates the host’s immune responses and gut microbiota and exhibits potent anti-cancer effects in ApcMin/+ mice. Pharmacol Res. 2022;176:106082.

[[22]] Wang A, Guan B, Shao C, et al. Qing-Xin-Jie-Yu Granule alleviates atherosclerosis by reshaping gut microbiota and metabolic homeostasis of ApoE-/- mice. Phytomedicine. 2022;103:154220.

[[23]] Li YJ, Liu RP, Ding MN, et al. Tetramethylpyrazine prevents liver fibrotic injury in mice by targeting hepatocyte-derived and mitochondrial DNA-enriched extracellular vesicles. Acta Pharmacol Sin. 2022;43(8):2026-2041.

[[24]] He JY, Hong Q, Chen BX, et al. Ginsenoside Rb1 alleviates diabetic kidney podocyte injury by inhibiting aldose reductase activity. Acta Pharmacol Sin. 2022;43(2):342-353.

[[25]] Que H, Hong W, Lan T, et al. Tripterin liposome relieves severe acute respiratory syndrome as a potent COVID-19 treatment. Signal Transduct Target Ther. 2022;7(1):399.

[[26]] Lin F, Wang Z, Xiang L, et al. Transporting hydrogel via Chinese acupuncture needles for lesion positioning therapy. Adv Sci (Weinh). 2022;9(17):e2200079.

[[27]] Sun D, Zou Y, Song L, et al.A cyclodextrin-based nanoformulation achieves co-delivery of ginsenoside Rg3 and quercetin for chemo-immunotherapy in colorectal cancer. Acta Pharm Sin B. 2022;12(1):378-393.

[[28]] Li L, Li Q, Gui L, et al. Sequential gastrodin release PU/n-HA composite scaffolds reprogram macrophages for improved osteogenesis and angiogenesis. Bioact Mater. 2022;19:24-37.

[[29]] Lu P, Li J, Liu C, et al. Salvianolic acid B dry powder inhaler for the treatment of idiopathic pulmonary fibrosis. Asian [J] Pharm Sci. 2022;17(3):447-461.

[[30]] Liu C, Yan X, Zhang Y, et al.Oral administration of turmeric-derived exosome-like nanovesicles with anti-inflammatory and pro-resolving bioactions for murine colitis therapy. J Nanobiotechnology. 2022;20(1):206.

[[31]] Yang H, Li Q, Li L, et al. Gastrodin modified polyurethane conduit promotes nerve repair via optimizing Schwann cells function. Bioact Mater. 2021;8:355-367.

[[32]] Geng Y, Xiang J, Shao S, et al. Mitochondria-targeted polymer-celastrol conjugate with enhanced anticancer efficacy. [J] Control Release. 2022;342:122-133.

[[33]] Xie C, Zhuang XX, Niu Z, et al. Amelioration of Alzheimer’s disease pathology by mitophagy inducers identified via machine learning and a cross-species workflow. Nat Biomed Eng. 2022;6(1):76-93.

[[34]] Zhang M, Yi Y, Gao BH, et al. Functional characterization and protein engineering of a triterpene 3-/6-/2’-O-glycosyltransferase reveal a conserved residue critical for the regiospecificity. Angew Chem Int Ed Engl. 2022;61(8):e202113587.

[[35]] Kerkovius JK, Stegner A, Turlik A, et al. A pyridine dearomatization approach to the Matrine-Type Lupin alkaloids. [J] Am Chem Soc. 2022;144(35):15938-15943.

[[36]] Hansen NL, Kjaerulff L, Heck QK, et al. Tripterygium wilfordii cytochrome P450s catalyze the methyl shift and epoxidations in the biosynthesis of triptonide. Nat Commun. 2022;13(1):5011.

[[37]] Wu XM, Guan QY, Han YB, et al. Regeneration of phytochemicals by structure-driven organization of microbial biosynthetic steps. Angew Chem Int Ed Engl. 2022;61(8):e202114919.

[[38]] Péter A, Crisenza GEM, Procter DJ.Asymmetric total synthesis of(-)-Phaeocaulisin A. J Am Chem Soc. 2022;144(16):7457-7464.

[[39]] Liu S, Wei C, Liu T, et al. A heme-activatable probe and its application in the high-throughput screening of Plasmodium falciparum ring-stage inhibitors. Signal Transduct Target Ther. 2022;7(1):160.

[[40]] Zha W, Zhang F, Shao J, et al. Rationally engineering santalene synthase to readjust the component ratio of sandalwood oil. Nat Commun. 2022;13(1):2508.

[[41]] Wu J, Zhu W, Shan X, et al. Glycoside-specific metabolomics combined with precursor isotopic labeling for characterizing plant glycosyltransferases. Mol Plant. 2022;15(10):1517-1532.

[[42]] Zhong C, Chen C, Gao X, et al.Multi-omics profiling reveals comprehensive microbe-plant-metabolite regulation patterns for medicinal plant Glycyrrhiza uralensis Fisch. Plant Biotechnol J. 2022;20(10):1874-1887.

[[43]] Liu S, Wang Y, Shi M, et al. SmbHLH60 and SmMYC2 antagonistically regulate phenolic acids and anthocyanins biosynthesis in Salvia miltiorrhiza. [J] Adv Res. 2022;42:205-219.

[[44]] Wang HD, Wang HM, Wang XY, et al.A novel hybrid scan approach enabling the ion-mobility separation and the alternate data-dependent and data-independent acquisitions (HDDIDDA): its combination with off-line two-dimensional liquid chromatography for comprehensively characterizing the multicomponents from Compound Danshen Dripping Pill. Anal Chim Acta. 2022;1193:339320.

[[45]] Liao B, Shen X, Xiang L, et al. Allele-aware chromosome-level genome assembly of Artemisia annua reveals the correlation between ADS expansion and artemisinin yield. Mol Plant. 2022;15(8):1310-1328.

[[46]] Shen Y, Li W, Zeng Y, et al. Chromosome-level and haplotype-resolved genome provides insight into the tetraploid hybrid origin of patchouli. Nat Commun. 2022;13(1):3511.

[[47]] Lv Z, Li J, Qiu S, et al. The transcription factors TLR1 and TLR2 negatively regulate trichome density and artemisinin levels in Artemisia annua. [J] Integr Plant Biol. 2022;64(6):1212-1228.

[[48]] Shu G, Tang Y, Yuan M, et al.Molecular insights into AabZIP1-mediated regulation on artemisinin biosynthesis and drought tolerance in Artemisia annua. Acta Pharm Sin B. 2022;12(3):1500-1513.

[[49]] Fan Y, Cao X, Zhang M, et al.Quantitative comparison and chemical profile analysis of different medicinal parts of Perilla frutescens (L.) Britt. from different varieties and harvest periods. J Agric Food Chem. 2022;70(28):8838-8853.

[[50]] Guo M, Pang X, Xu Y, et al. Plastid genome data provide new insights into the phylogeny and evolution of the genus Epimedium. [J] Adv Res. 2021;36:175-185.

[[51]] Li X, Xu D, Tu JF, et al. The “top 50 high impact researches of traditional medicine” published in 2021. Acupunct Herb Med. 2023;3(4):232-243.

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2024 Acupuncture and Herbal Medicine