Localization of bcl-2 antiapoptotic protein in human placenta

Abstract

The aim of this investigation was to study the distribution of bcl-2 antiapoptotic protein in various structures of human pla-centa using immunocytochemical methods. Syncytiotrophoblast was found to have the greatest bcl-2 immunorcactivity, while cytotrophoblastic elements, connective tissue cells of the villi and the blood vessel walls were bcl-2-negative. It is suggested that accumulation of bcl-2 in the syncytiotrophoblast may reflect its high resistance to detrimental factors.

Keywords

bcl-2 / placenta / apoptosis / bcl-2 / man

References

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