Decontamination of mobile phones and electronic devices for health care professionals using a chlorhexidine/carbomer 940® gel

Frontiers of Chemical Science and Engineering ›› 2019, Vol. 13 ›› Issue (1) : 192-198.

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Frontiers of Chemical Science and Engineering ›› 2019, Vol. 13 ›› Issue (1) : 192-198. DOI: 10.1007/s11705-018-1728-5
RESEARCH ARTICLE

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Decontamination of mobile phones and electronic devices for health care professionals using a chlorhexidine/carbomer 940® gel

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Abstract

Though they reduce microorganism growth, current hospital disinfectants also damage many of today’s modern electronic devices such as tablets and smartphones. Herein, the efficacy of a new chlorhexidine digluconate gel (CDG) was tested as a disinfectant for mobile and electronic devices in a clinical environment. Specifically, Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa and methicillin resistant Staphylococcus aureus were used to infect the screen of eight smartphones. The CDG was prepared at concentrations of 2%, 4% and 6%, and tested on paper disks infected with these bacteria before being tested on the smartphones. The devices were disinfected with the CDG gel (4%) at two times: immediately and after 5 min of the bacterial contamination. In all cases, the CDG gel eliminated 100% of gram-positive and gram-negative microorganisms compared to the control (without any agent). In addition, the gel did not damage the smartphones. Therefore, our study suggests that the CDG gel may be applied to disinfect a wide range of electronic devices for health care professionals in the hospital environment.

Keywords

smartphones / disinfection / clinical environment / chlorhexidine / bacteria

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. . Frontiers of Chemical Science and Engineering. 2019, 13(1): 192-198 https://doi.org/10.1007/s11705-018-1728-5

参考文献

[1]
Madden G R, Weinstein R A, Sifri C D. Diagnostic stewardship for healthcare-associated infections: Opportunities and challenges to safely reduce test use. Infection Control and Hospital Epidemiology, 2018, 39(2): 214–218
CrossRef ADS Pubmed Google scholar
[2]
Grant M C, Yang D, Wu C L, Makary M A, Wick E C. Impact of enhanced recovery after surgery and fast track surgery pathways on healthcare-associated infections. Results from a systematic review and meta-analysis. Annals of Surgery, 2017, 265(1): 68–79
CrossRef ADS Pubmed Google scholar
[3]
Jasovský D, Littmann J, Zorzet A, Cars O. Antimicrobial resistance-a threat to the world’s sustainable development. Upsala Journal of Medical Sciences, 2016, 121(3): 159–164
CrossRef ADS Pubmed Google scholar
[4]
Lemmen S W, Häfner H, Zolldann D, Stanzel S, Lütticken R. Distribution of multi-resistant Gram-negative versus Gram-positive bacteria in the hospital inanimate environment. Journal of Hospital Infection, 2004, 56(3): 191–197
CrossRef ADS Pubmed Google scholar
[5]
Deak D, Outterson K, Powers J H, Kesselheim A S. Progress in the fight against multidrug-resistant bacteria? A review of U.S. food and drug administration—approved antibiotics, 2010–2015. Annals of Internal Medicine, 2016, 165(5): 363–372
CrossRef ADS Pubmed Google scholar
[6]
Kramer A, Schwebke I, Kampf G. How long do nosocomial pathogens persist on inanimate surfaces? A systematic review. BMC Infectious Diseases, 2006, 6(1): 130
CrossRef ADS Pubmed Google scholar
[7]
Hammon M, Kunz B, Dinzl V, Kammerer F J, Schwab S A, Bogdan C, Uder M, Schlechtweg P M. Practicability of hygienic wrapping of touchscreen operated mobile devices in a clinical setting. PLoS One, 2014, 9(9): e106445
CrossRef ADS Pubmed Google scholar
[8]
Zeglin L H. Stream microbial diversity in response to environmental changes: review and synthesis of existing research. Frontiers in Microbiology, 2015, 6(454): 454
Pubmed
[9]
Zakai S, Mashat A, Abumohssin A, Samarkandi A, Almaghrabi B, Barradah H, Jiman-Fatani A. Bacterial contamination of cell phones of medical students at King Abdulaziz University, Jeddah, Saudi Arabia. Journal of Microscopy and Ultrastructure, 2016, 4(3): 143–146
CrossRef ADS Google scholar
[10]
Sorensen J A, Doherty F M, Newman M G, Flemmig T F. Gingival enhancement in fixed prosthodontics. Part I: Clinical findings. Journal of Prosthetic Dentistry, 1991, 65(1): 100–107
CrossRef ADS Pubmed Google scholar
[11]
Jones C G. Chlorhexidine: Is it still the gold standard? Periodontology 2000, 1997, 15(1): 55–62
[12]
Supranoto S C, Slot D E, Addy M, Van der Weijden G A. The effect of chlorhexidine dentifrice or gel versus chlorhexidine mouthwash on plaque, gingivitis, bleeding and tooth discoloration: A systematic review. International Journal of Dental Hygiene, 2015, 13(2): 83–92
CrossRef ADS Pubmed Google scholar
[13]
Vitkov L, Hermann A, Krautgartner W D, Herrmann M, Fuchs K, Klappacher M, Hannig M. Chlorhexidine-induced ultrastructural alterations in oral biofilm. Microscopy Research and Technique, 2005, 68(2): 85–89
CrossRef ADS Pubmed Google scholar
[14]
Ferraz C C R, Gomes B P F A, Zaia A A, Teixeira F B, Souza-Filho F J. Comparative study of the antimicrobial efficacy of chlorhexidine gel, chlorhexidine solution and sodium hypochlorite as endodontic irrigants. Brazilian Dental Journal, 2007, 18(4): 294–298
CrossRef ADS Pubmed Google scholar
[15]
Kim J Y, Song J Y, Lee E J, Park S K. Rheological properties and microstructures of Carbopol gel network system. Colloid & Polymer Science, 2003, 281(7): 614–623
CrossRef ADS Google scholar
[16]
Zheng Y, Ouyang W Q, Wei Y P, Syed S F, Hao C S, Wang B Z, Shang Y H. Effects of Carbopol® 934 proportion on nanoemulsion gel for topical and transdermal drug delivery: A skin permeation study. International Journal of Nanomedicine, 2016, 11: 5971–5987
CrossRef ADS Pubmed Google scholar
[17]
Mathew J I, Cadnum J L, Sankar T, Jencson A L, Kundrapu S, Donskey C J. Evaluation of an enclosed ultraviolet-C radiation device for decontamination of mobile handheld devices. American Journal of Infection Control, 2016, 44(6): 724–726
CrossRef ADS Pubmed Google scholar
[18]
Gashaw M, Abtew D, Addis Z. Prevalence and antimicrobial susceptibility pattern of bacteria isolated from mobile phones of health care professionals working in gondar town health centers. International Scholarly Research Notices, 2014, 2014: 1–6
[19]
Shakir I A, Patel N H, Chamberland R R, Kaar S G. Investigation of cell phones as a potential source of bacterial contamination in the operating room. Journal of Bone and Joint Surgery, 2015, 97(3): 225–231
CrossRef ADS Pubmed Google scholar
[20]
A-sasutjarit R, Sirivat A, Vayumhasuwan P. Viscoelastic properties of Carbopol 940 gels and their relationships to piroxicam diffusion coefficients in gel bases. Pharmaceutical Research, 2005, 22(12): 2134–2140
CrossRef ADS Pubmed Google scholar
[21]
Jana S, Manna S, Nayak A K, Sen K K, Basu S K. Carbopol gel containing chitosan-egg albumin nanoparticles for transdermal aceclofenac delivery. Colloids and Surfaces B: Biointerfaces, 2014, 114: 36–44
CrossRef ADS Pubmed Google scholar
[22]
Barry B W, Meyer M C. The rheological properties of carbopol gels. I. Continuous shear and creep properties of carbopol gels. International Journal of Pharmaceutics, 1979, 2(1): 1–25
CrossRef ADS Google scholar
[23]
Santos I R M, Moreira A C A, Costa M G C, Barbosa M C. Effect of 0.12% chlorhexidine in reducing microorganisms found in aerosol used for dental prophylaxis of patients submitted to fixed orthodontic treatment. Dental Press Journal of Orthodontics, 2014, 19(3): 95–101
CrossRef ADS Pubmed Google scholar
[24]
McDonnell G, Russell A D. Antiseptics and disinfectants: activity, action, and resistance. Clinical Microbiology Reviews, 1999, 12(1): 147–179
Pubmed
[25]
Perioli L, Ambrogi V, Angelici F, Ricci M, Giovagnoli S, Capuccella M, Rossi C. Development of mucoadhesive patches for buccal administration of ibuprofen. Journal of Controlled Release, 2004, 99(1): 73–82
CrossRef ADS Pubmed Google scholar
[26]
Velasquez Reyes D C, Bloomer M, Morphet J. Prevention of central venous line associated bloodstream infections in adult intensive care units: A systematic review. Intensive & Critical Care Nursing, 2017, 43: 12–22
CrossRef ADS Pubmed Google scholar

Acknowledgements

The authors are very grateful to the team from the bacteriology sector of the Clinical Laboratory of University Hospital of West of Paraná for laboratory evaluation and aid of the application of data collection. Anderson Oliveira Lobo and Fernanda Roberta Marciano would like to thank the National Council for Scientific and Technological Development (CNPq grant numbers: AOL ‒ 303752/2017-3 and FRM ‒ 304133/2017-5), Coordination for the Improvement of Higher Education Personnel (CAPES, grant numbers 88881.120138/2016-01 and 88881.120221/2016-01) and to the Universidade Brasil for scholarships. English language corrections were provided by Ms. Jessica Fitzgerald, a writing consultant for the Chemical Engineering Writing Center at North-eastern University.
This study did not count on funding fomenting agencies. There are no conflicts of interest by the authors.

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2018 Higher Education Press and Springer-Verlag GmbH Germany, part of Springer Nature
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